| Author | Zanella, Louise | |
| Author | Otsuki, Koko | |
| Author | Marin, Michel Abanto | |
| Author | Bendet, Izidro | |
| Author | Vicente, Ana Carolina | |
| Access date | 2018-11-08T14:00:37Z | |
| Available date | 2018-11-08T14:00:37Z | |
| Document date | 2012 | |
| Citation | ZANELLA, Louise; et al. Complete Genome Sequence of Central Africa Human T-Cell Lymphotropic Virus Subtype 1b. Journal of Virology, v.86, n.22, p.12451, Nov. 2012. | pt_BR |
| ISSN | 0022-538X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/29951 | |
| Language | eng | pt_BR |
| Publisher | American Society for Microbiology | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Sequência Completa do Genoma | pt_BR |
| Subject in Portuguese | Subtipo do Vírus Linfotrópico | pt_BR |
| Subject in Portuguese | Vírus Linfotrópico de Células T Humana 1b | pt_BR |
| Subject in Portuguese | África Central | pt_BR |
| Title | Complete Genome Sequence of Central Africa Human T-Cell Lymphotropic Virus Subtype 1b | pt_BR |
| Type | Article | |
| DOI | 10.1128/JVI.02258-12 | |
| Abstract | Human T-lymphotropic virus type 1 (HTLV-1) has a global spread, and it is estimated that around 20 million persons are infected.
Seven major genetic subtypes are recognized. However, there are complete genomes only from the HTLV-1a (cosmopolitan)
and HTLV-1c (Melanesian) subtypes. Here, the first full-length genome of an HTLV-1b strain, a subtype so far restricted to
Central African countries, is revealed. The genome size of HTLV-1b SF26, a strain isolated in Brazil, was determined to be 8,267
bp. The genomic analysis showed that all characteristic regions and genes of a prototypic HTLV-1 virus are conserved. This genome
can provide information for further studies on the evolutionary history and pathogenic potential of this human oncovirus. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Sérgio Franco Medicina Diagnóstica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Complete Genome Sequence | pt_BR |
| Subject | Human T-Cell | pt_BR |
| Subject | Lymphotropic Virus Subtype 1b | pt_BR |
| Subject | Central Africa | pt_BR |
| e-ISSN | 1098-5514 | |
