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OCCURRENCE AND COMPOSITION OF CLASS 1 AND CLASS 2 INTEGRONS IN CLINICAL AND ENVIRONMENTAL O1 AND NON-O1/NON-O139 VIBRIO CHOLERAE STRAINS FROM THE BRAZILIAN AMAZON
Sá, Lena Lillian Canto de et al. | Date Issued: 2010
Author
Sá, Lena Lillian Canto de
Fonseca, Érica Lourenço da
Pellegrini, Maíra
Freitas, Fernanda
Loureiro, Edvaldo Carlos Brito
Vicente, Ana Carolina Paulo
Affilliation
Instituto Evandro Chagas. Seção de Meio Ambiente. Laboratório de Microbiologia Ambiental. Belém, PA, Brasil.
Instituto Evandro Chagas. Seção de Bacteriologia e Micologia. Laboratório de Enteroinfecções Bacterianas. Belém, PA, Brasil.
Instituto Evandro Chagas. Seção de Bacteriologia e Micologia. Laboratório de Enteroinfecções Bacterianas. Belém, PA, Brasil.
Instituto Evandro Chagas. Seção de Bacteriologia e Micologia. Laboratório de Enteroinfecções Bacterianas. Belém, PA, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ. Brasil.
Instituto Evandro Chagas. Seção de Bacteriologia e Micologia. Laboratório de Enteroinfecções Bacterianas. Belém, PA, Brasil.
Abstract
This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens.
Keywords in Portuguese
Vibrio cholerae
Amazônia brasileira
Integrons
classe 2
 
Keywords
Vibrio cholerae
class 2 integron
Amazon
 
DeCS
Integrons
Publisher
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
Citation
SÁ, Lena Lilian Canto de; et al. Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon. Mem Inst Oswaldo Cruz, v.105, n.2, p.229-232, Mar. 2010.
ISSN
0074-0276