Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/30400
Title: Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study
Authors: Shivakoti, Rupak
Gupte, Nikhil
Tripathy, Srikanth
Poongulali, Selvamuthu
Kanyama, Cecilia
Berendes, Sima
Cardoso, Sandra W
Santos, Breno R
La Rosa, Alberto
Mwelase, Noluthando
Pillay, Sandy
Samaneka, Wadzanai
Riviere, Cynthia
Sugandhavesa, Patcharaphan
Bollinger, Robert C
Balagopal, Ashwin
Semba, Richard D
Christian, Parul
Campbell, Thomas B
Gupta, Amita
Affilliation: Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA./ Columbia University Mailman School of Public Health. Department of Epidemiology. New York, NY, USA.
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA.
National AIDS Research Institute. Pune, India./ National Institute of Research in Tuberculosis. Chennai, India.
YR Gaitonde Center for AIDS Research and Education. Chennai, India.
UNC Lilongwe. Lilongwe, Malawi.
Johns Hopkins University Research Project. Malawi College of Medicine. Blantyre, Malawi./ Liverpool School of Tropical Medicine. Liverpool, UK.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Hospital Nossa Senhora de Conceição. Porto Alegre, RS, Brasil.
Asociacion Civil Impacta Salud y Educacion. Lima, Peru
University of Witwatersrand. Department of Medicine. Johannesburg, South Africa.
Durban University of Technology. Durban International Clinical Research Site. Durban, South Africa.
University of Zimbabwe. Clinical Research Centre. Harare, Zimbabwe.
Les Centres GHESKIO. Port-Au-Prince, Haiti.
Research Institute for Health Sciences. Chiang Mai, Thailand.
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA./ Johns Hopkins Bloomberg School of Public Health. Department of International Health. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA.
Johns Hopkins University. School of Medicine. Department of Ophthalmology. Baltimore, MD, USA.
Johns Hopkins Bloomberg School of Public Health. Department of International Health. Baltimore, MD, USA./ Bill and Melinda Gates Foundation. Seattle, USA.
University of Colorado. School of Medicine. Division of Infectious Diseases. Department of Medicine. Aurora, CO, USA.
Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, MD, USA.
Abstract: Various individual biomarkers of inflammation and micronutrient status, often correlated with each other, are associated with adverse treatment outcomes in human immunodeficiency virus (HIV)-infected adults. The objective of this study was to conduct exploratory factor analysis (EFA) on multiple inflammation and micronutrient biomarkers to identify biomarker groupings (factors) and determine their association with HIV clinical treatment failure (CTF) and incident active tuberculosis (TB).
Keywords: Antiretroviral therapy
Exploratory factor analysis
HIV
IL-18
Inflammation
Tuberculosis
Issue Date: 2018
Publisher: BMC
Citation: SHIVAKOTI, R. et al. Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study. BMC medicine, v. 16, n. 1, p. 161, 2018.
Description: NWCS 319 and PEARLS Study Team are part of the authors group.
DOI: 10.1186/s12916-018-1150-3
ISSN: 1741-7015
Copyright: open access
Appears in Collections:INI - Artigos de Periódicos

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