| Author | Costa, Elis R. Dalla | |
| Author | Ribeiro, Marta O. | |
| Author | Silva, Márcia S. N. | |
| Author | Arnold, Liane S. | |
| Author | Rostirolla, Diana C. | |
| Author | Cafrune, Patricia I. | |
| Author | Espinoza, Roger C. | |
| Author | Palaci, Moises | |
| Author | Telles, Maria A. | |
| Author | Ritacco, Viviana | |
| Author | Suffys, Philip N. | |
| Author | Lopes, Maria L. | |
| Author | Campelo, Creuza L. | |
| Author | Miranda, Silvana S. | |
| Author | Kremer, Kristin | |
| Author | Silva, Pedro E. Almeida da | |
| Author | Fonseca, Leila de Souza | |
| Author | Ho, John L. | |
| Author | Kritski, Afrânio L. | |
| Author | Rossetti, Maria L. R. | |
| Access date | 2019-01-10T13:50:36Z | |
| Available date | 2019-01-10T13:50:36Z | |
| Document date | 2009 | |
| Citation | DALLA COSTA, Elis R. et al. Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America. BMC Microbiology, v. 9, n. 39, p. 1-11, Feb. 2009. | pt_BR |
| ISSN | 1471-2180 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30961 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Mycobacterium tuberculosis | pt_BR |
| Subject in Portuguese | Mutações | pt_BR |
| Subject in Portuguese | Genes katG, oxyR-ahpC e inhA | pt_BR |
| Subject in Portuguese | Linhagens clínicas | pt_BR |
| Subject in Portuguese | Amílias de espoligotipos | pt_BR |
| Subject in Portuguese | América do Sul | pt_BR |
| Subject in Portuguese | Tuberculose | pt_BR |
| Title | Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America | pt_BR |
| Type | Article | |
| DOI | 10.1186/1471-2180-9-39 | |
| Abstract | Mutations associated with resistance to rifampin or streptomycin have been
reported for W/Beijing and Latin American Mediterranean (LAM) strain families of Mycobacterium tuberculosis. A few studies with limited sample sizes have separately evaluated mutations in katG, ahpC and inhA genes that are associated with isoniazid (INH) resistance. Increasing prevalence of
INH resistance, especially in high tuberculosis (TB) prevalent countries is worsening the burden of TB control programs, since similar transmission rates are noted for INH susceptible and resistant M. tuberculosis strains. | pt_BR |
| Affilliation | Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Luterana University of Brazil. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Federal University of Rio Grande do Sul. Porto Alegre, RS, Brazil. | pt_BR |
| Affilliation | Blufstein Clinic Laboratory. Lima, Peru. | pt_BR |
| Affilliation | Federal University of Espírito Santo. Vitória, ES, Brazil. | pt_BR |
| Affilliation | Adolfo Lutz Institute. São Paulo, SP, Brazil. | pt_BR |
| Affilliation | Instittuto Nacional Enfermedades Infecciosas. Servicio de Micobacterias. Argentina. | pt_BR |
| Affilliation | Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Evandro Chagas Institute. Manaus, AM, Brazil. | pt_BR |
| Affilliation | LACEN. Fortaleza, CE, Brazil. | pt_BR |
| Affilliation | Federal University of Minas Gerais. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | National Institute for Public Health and the Environment. Mycobacteria Reference Unit. Amsterdã, Netherlands. | pt_BR |
| Affilliation | Federal Foundation of Rio Grande. Porto Alegre, RS, Brazil. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Cornell University, Ithaca. New York, USA. | pt_BR |
| Affilliation | Federal University of Rio de Janeiro. Tuberculosis Academic Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | State Foundation for Production and Research in Health. Porto Alegre, RS, Brazil / Luterana University of Brazil. Rio de Janeiro, RJ, Brazil / Fundação Estadual de Produção e Pesquisa em Saúde. Centro de Desenvolvimento Científico e Tecnológico. Porto Alegre, RS, Brazil. | pt_BR |
| Subject | Mycobacterium tuberculosis | pt_BR |
| Subject | OxyR-ahpC and inhA genes | pt_BR |
| Subject | Mutations | pt_BR |
| Subject | Spoligotype families | pt_BR |
| Subject | Tuberculosis | pt_BR |
| Subject | South America | pt_BR |
| Subject | Clinical strains | pt_BR |
