| Author | Martins, Ademir Jesus | |
| Author | Lima, José Bento Pereira | |
| Author | Peixoto, Alexandre Afranio | |
| Author | Valle, Denise | |
| Access date | 2019-01-10T14:45:51Z | |
| Available date | 2019-01-10T14:45:51Z | |
| Document date | 2009 | |
| Citation | MARTINS, Ademir Jesus et al. Frequency of Val1016Ile mutation in the voltage-gated sodium channel gene of Aedes aegypti Brazilian populations. Tropical Medicine and International Health, v. 14, n. 11, p. 1351-1355, Nov. 2009. | pt_BR |
| ISSN | 1360-2276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/30966 | |
| Language | eng | pt_BR |
| Publisher | Wiley 12 Months | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Resistência a piretróide | pt_BR |
| Subject in Portuguese | Gene do canal de sódio | pt_BR |
| Subject in Portuguese | Mutação kdr | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Frequency of Val1016Ile mutation in the voltage-gated sodium channel gene of Aedes aegypti Brazilian populations | pt_BR |
| Type | Article | |
| DOI | 10.1111/j.1365-3156.2009.02378.x | pt_BR |
| Abstract | One of the major insect pyrethroid resistance mechanisms affects its target site, the voltage-gated sodium channel (Na(v)). In Aedes aegypti, the Val1016Ile substitution of the AaNa(v) gene is associated to resistance in several Latin American countries. Genotyping of susceptible and resistant mosquitoes from seven Brazilian localities detected the 1016Ile mutation in five populations with a higher frequency of this substitution in resistant specimens in all cases. Furthermore, analysis of nine additional field populations revealed that five also presented the 1016Ile mutation. Our data suggest a recent dissemination and involvement of this substitution with pyrethroid resistance in Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Pyrethroid resistance | pt_BR |
| Subject | Kdr mutation | pt_BR |
| Subject | Sodium channel gene | pt_BR |
| Subject | Brazil | pt_BR |
| e-ISSN | 10.1111/j.1365-3156.2009.02378.x | |
| e-ISSN | 1365-3156 | |
| Embargo date | 2030-01-01 | |
