| Author | Costa, Emmanoel Vilaça | |
| Author | Pinheiro, Maria Lúcia Belém | |
| Author | Silva, Jefferson Rocha de Andrade | |
| Author | Maia, Beatriz Helena Lameiro de Noronha Sales | |
| Author | Duarte, Marta Cristina Teixeira | |
| Author | Amaral, Ana Cláudia Fernandes | |
| Author | Machado, Gérzia Maria de Carvalho | |
| Author | Leon, Leonor Laura | |
| Access date | 2019-01-15T14:05:53Z | |
| Available date | 2019-01-15T14:05:53Z | |
| Document date | 2009 | |
| Citation | COSTA, Emmanoel Vilaça et al. Antimicrobial and Antileishmanial acvtivity of essential oil from the leaves of Annona foetida. Qumi. Nova, v. 32, n. 1, p. 78-81, 2009. | pt_BR |
| ISSN | 0100-4042 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/31040 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Química | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Annona foetida | pt_BR |
| Subject in Portuguese | Composição de óleo essencial | pt_BR |
| Subject in Portuguese | Atividades antimicrobiana e antileishmanial | pt_BR |
| Title | Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (ANNONACEAE) | pt_BR |
| Type | Article | |
| Abstract | The essential oil from leaves of Annona foetida obtained by hydrodistillation was analyzed by GC/FID and GC/MS. The results showed that the major constituents were bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages. | pt_BR |
| Affilliation | Universidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Paraná. Departamento de Química. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Campinas. Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Farmanguinhos. Departamento de Produtos Naturais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Annona foetida | pt_BR |
| Subject | Antimicrobial and antileishmanial activities | pt_BR |
| Subject | Essential oil composition | pt_BR |
| e-ISSN | 1678-7064 | |
