| Author | Ribeiro, Luciano C. | |
| Author | Souto, Francisco Jose Dutra | |
| Author | Espírito-Santo, Márcia P. do | |
| Author | Oliveira, Rodrigo G. | |
| Author | Lampe, Elisabeth | |
| Access date | 2019-01-17T15:18:17Z | |
| Available date | 2019-01-17T15:18:17Z | |
| Document date | 2009 | |
| Citation | RIBEIRO, Luciano C. et al. An autochthonous case of hepatitis C virus genotype 5a in Brazil: phylogenetic analysis. Archives of Virology, v. 154, p. 665-670, Mar. 2009. | pt_BR |
| ISSN | 0304-8608 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/31118 | |
| Language | eng | pt_BR |
| Publisher | Springer-Verlag | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Vírus da Hepatite C | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Subject in Portuguese | Caso autóctone | pt_BR |
| Subject in Portuguese | Genótipo 5a | pt_BR |
| Subject in Portuguese | Análise filogenética | pt_BR |
| Title | An autochthonous case of hepatitis C virus genotype 5a in Brazil: phylogenetic analysis | pt_BR |
| Type | Article | |
| DOI | 10.1007/s00705-008-0279-3 | |
| Abstract | Genotype 5 of hepatitis C virus (HCV) has been rarely identified in South America. A female of African descent who never left Brazil was found to be infected by this genotype in Mato Grosso state, Central Brazil. The patient denied drug injections and revealed that she had received blood transfusions several years before. One of her blood donors was identified and tested negative for anti-HCV and HCV RNA, as were her husband and offspring. Phylogenetic analysis of the E1 and NS5B regions confirmed that this HCV strain belonged to genotype 5a. However, the E1 region analysis indicates that our strain is not closely related to any sequences of genotype 5a from other geographical areas, diverging from the African and European subclades known so far. These data suggest that genotype 5a HCV might have been circulating at a low level in Brazil longer than previously supposed. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Ciências Médicas. Departamento de Clínica Médica. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Ciências Médicas. Departamento de Clínica Médica. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Technical University of Denmark. Center for Biological Sequence Analysis. Lingby, Denmark. | pt_BR |
| Affilliation | Technical University of Denmark. Center for Biological Sequence Analysis. Lingby, Denmark. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Autochthonous case | pt_BR |
| Subject | Hepatitis C virus | pt_BR |
| Subject | Genotype 5a | pt_BR |
| Subject | Brazil | pt_BR |
| Subject | Phylogenetic analysis | pt_BR |
| e-ISSN | 1432-8798 | |
| Embargo date | 2030-01-01 | |
