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HISTOPATHOLOGY OF VALVES IN INFECTIVE ENDOCARDITIS, DIAGNOSTIC CRITERIA AND TREATMENT CONSIDERATIONS
Brandão, Tatiana J. D. et al. | Date Issued: 2017
Author
Brandão, Tatiana J. D.
Silva, Carolina A. Januario da
Correia, Marcelo G.
Zappa, Monica
Abrantes, Jaime Antonio
Dantas, Angela M. R.
Golebiovski, Wilma
Barbosa, Giovanna Ianini F.
Weksler, Clara
Lamas, Cristiane C.
Affilliation
Instituto Nacional de Cardiologia. Heart Valve Disease Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Heart Valve Disease Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Biostatistics Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Pathology Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Microbiology Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Microbiology Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Heart Valve Disease Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Infection Control Unit. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Heart Valve Disease Department. Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Cardiologia. Heart Valve Disease Department. Rio de Janeiro, RJ, Brazil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio. Duque de Caxias, RJ, Brasil / Instituto Nacional de Cardiologia. Valvular Disease Department. Rio de Janeiro, RJ, Brazil.
Abstract
Infective endocarditis (IE) is a severe disease. Pathogen isolation is fundamental so as to treat effectively and reduce morbidity and mortality. Blood and valve culture and histopathology (HP) are routinely employed for this purpose. Valve HP is the gold standard for diagnosis.
Keywords
Infective endocarditis
Blood culture
Valve culture
Valve histopathology
Diagnostic criteria
Sensitivity
Specificity
Valve replacement surgery
Antibiotic therapy
 
Publisher
Springer Verlag
Citation
BRANDÃO, Tatiana J. D. et al. Histopathology of valves in infective endocarditis, diagnostic criteria and treatment considerations. Infection, v. 45, p. 199-207, 2017.
DOI
10.1007/s15010-016-0953-4
ISSN
0300-8126