Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/31692
Title: Human CCR5Δ32 (rs333) polymorphism has no influence on severity and mortality of influenza A(H1N1)pdm09 infection in Brazilian patients from the post pandemic period
Authors: Matos, Aline R.
Martins, Jéssica S. C. C.
Oliveira, Maria de Lourdes A.
Garcia, Cristiana C.
Siqueira, Marilda M.
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Centro Nacional de Influenza (WHO). Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Centro Nacional de Influenza (WHO). Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Centro Nacional de Influenza (WHO). Rio de Janeiro, RJ, Brasil.
Abstract: Influenza is an acute and highly contagious viral respiratory infection that causes significant morbidity and mortality. The identification of host genetic factors associated with susceptibility and severity of influenza virus infection is of paramount importance. Previous studies evaluating the potential involvement of the CCR5Δ32 polymorphism (rs333), a 32 base pair deletion in CC motif chemokine receptor 5 (CCR5) gene, in severity and mortality of influenza A(H1N1)pdm09 infected individuals have been reported, but their results are quite conflicting.
Keywords: A(H1N1)Pdm09
CCR5delta32
Host susceptibility
Influenza
Mortality
Severity
Brazil
keywords: Gripe
Suscetibilidade do hospedeiro
Mortalidade
Gravidade
Brasil
Issue Date: 2019
Publisher: Elsevier
Citation: MATOS, Aline R. et al. Human CCR5Δ32 (rs333) polymorphism has no influence on severity and mortality of influenza A(H1N1)pdm09 infection in Brazilian patients from the post pandemic period. Infection, Genetics and Evolution, v. 67, p. 55-59, 2019.
DOI: 10.1016/j.meegid.2018.10.024
ISSN: 1567-1348
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
jessicacc_martins_etal_IOC_2018.pdf234.95 kBAdobe PDF    Request a copy



FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.