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2020-01-31
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- INI - Artigos de Periódicos [3394]
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HIGH VARIABILITY WITHIN CANDIDA ALBICANS TRANSCRIPTION FACTOR RLM1: ISOLATES FROM VULVOVAGINAL INFECTIONS SHOW A CLEAR BIAS TOWARD HIGH MOLECULAR WEIGHT ALLELES
Author
Affilliation
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
National and Kapodistrian University of Athens. Medical School. Dept. of Microbiology. Mycology Research Laboratory. Athens, Greece.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
National and Kapodistrian University of Athens. Medical School. Dept. of Microbiology. Mycology Research Laboratory. Athens, Greece.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
University of Minho. Centre of Molecular and Environmental Biology (CBMA). Department of Biology. Braga, Portugal.
Abstract
Previous studies have correlated the severity of recurrent vulvovaginal Candida infections (VVC) and balanitis in patients from China with the presence of some dominant genotypes at the ORF RLM1. Here we tested VVC vs non-VVC isolates from Portugal, Brazil and Greece and, although the same genotypes were identified in VVC isolates, they were present in only five out of 150 strains. However, this analysis showed that VVC isolates presented a higher percentage of genotypes with similar high molecular weight alleles, in comparison with strains isolated from other biological sources.
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