Late identification of Chikungunya virus in the central nervous system of a 2-month-old infant: persistence of maternal-neonatal infection?

Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Neonatologia. Rio de Janeiro, RJ, Brasil.
Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Neonatologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Doenças Febris Agudas. Rio de Janeiro, RJ, Brasil.

Abstract

We report here a probable case of vertical transmission of chikungunya infection with confirmed maternal viremia close to labor that led to severe infection in the newborn. The newborn progressed with cutaneous lesions and irritability 2 months after vertical transmission, when chikungunya virus was detected in the infant's CSF by a molecular diagnostic test (real-time polymerase chain reaction).

Keywords

Chikungunya
Neonatal encephalopathy
Neonatal sepsis
Newborn
Vertical transmission

Publisher

Oxford University Press

Citation

FERREIRA, Fátima C. P. A. Di Maio. Late identification of Chikungunya virus in the central nervous system of a 2-month-old infant: persistence of maternal-neonatal infection? Journal of the Pediatric Infectious Diseases Society, v. 20, n. 20, p. 1-4, 2019.

DOI

10.1093/jpids/piy135

ISSN

2048-7193

Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/31895

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