Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/32130
Title: Response to azolic antifungal agents for treating feline sporotrichosis
Authors: Pereira, S. A.
Passos, S. R. L.
Silva, J. N.
Gremião, I. D. F.
Figueiredo, F. B.
Teixeira, J. L.
Monteiro, P. C. F.
Schubach, T. M. P.
Affilliation: Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Abstract: The effectiveness and safety of treatment with ketoconazole and itraconazole were compared in 773 sporotrichosis-infected cats over a four-year period (2002 to 2005). Five hundred and ninety-eight cats received oral ketoconazole and 175 received oral itraconazole. Treatment was successful in 238 (30.8 per cent) cats, of which 171 (28.6 per cent) of 598 received 13.5 to 27.0 mg/kg/day ketoconazole and 67 (38.3 per cent) of 175 received 8.3 to 27.7 mg/kg/day itraconazole. Adverse effects were reported in 306 (39.6 per cent) of the cats, 105 (13.6 per cent) died and 430 (55.6 per cent) dropped out of treatment or were still under treatment at the time of data analysis.
Keywords: Feline sporotrichosis
Azolic antifungal
Issue Date: 2010
Publisher: BMJ Publishing Group
Citation: PEREIRA, S. A. et al. Response to azolic antifungal agents for treating feline sporotrichosis. Veterinary Record, v. 166, p. 290-294, 2010.
DOI: 10.1136/vr.b4752
ISSN: 0042-4900
Copyright: restricted access
Appears in Collections:INI - Artigos de Periódicos

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