Genotyping of Panamanian Trypanosoma cruzi stocks using the calmodulin 3'UTR polymorphisms

Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.
Instituto Conmemorativo Gorgas de Estudios de la Salud. Panama, Panama.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.
Instituto Conmemorativo Gorgas de Estudios de la Salud. Panama, Panama.
University of Panama. Faculty of Medicine. Center for Research and Diagnosis of Parasitic Diseases. Panama, Panama / Instituto Conmemorativo Gorgas de Estudios de la Salud. Panama, Panama.

Abstract

Mutations in the 3' untranslated region of calmodulin gene have recently been reported to be specific to different Trypanosoma cruzi lineages. In the present report, this molecular marker was used to genotype 24 T. cruzi isolates from humans and vectors from different endemic areas in Panama. The finding of solely T. cruzi I genotype might explain the low morbidity of Chagas' disease in the region when compared to other countries in Latin America.

Keywords in Portuguese

Trypanosoma cruzi
Estoques panamenhos
Genotipagem
Polimorfismos calmodulin 3′UTR

Keywords

Trypanosoma cruzi
Panamanian Trypanosoma cruzi stocks
Genotyping
Calmodulin 3′UTR polymorphisms

Publisher

Springer

Citation

BRANDÃO, Adeilton et al. Genotyping of Panamanian Trypanosma cruzi stocks using the calmodium 3`UTR polymorphisms. Parasitol Res., v. 102, p. 523–526, 2008.

DOI

10.1007/s00436-007-0775-5

ISSN

0932-0113

Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/32159

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Copyright

Restricted access

Embargo date

2022-01-01

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