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2019-10-05
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ULCERATIONS DUE TO METHOTREXATE TOXICITY IN A PSORIASIS PATIENT
Souza, Claudia Fernanda Dias et al. | Date Issued: 2016
Author
Souza, Claudia Fernanda Dias
Silva, Talita Fonseca Medeiros da
Quintella, Leonardo Pereira
Avelleira, João Carlos Regazzi
Zarco Suarez, Olga Milena
Gorenstein, Ana Carolina Lourenço Araújo
Affilliation
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil.
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil.
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil.
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil.
Santa Casa da Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil.
Abstract
Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription.
Keywords
Methotrexate
Psoriasis
Therapeutics
Toxicity
 
Publisher
Sociedade Brasileira de Dermatologia
Citation
SOUZA, Claudia Fernanda Dias et al. Ulcerations due to methotrexate toxicity in a psoriasis patient. Anais Brasileiros de Dermatologia, v. 91, n. 3, p. 375-377, 2016.
DOI
10.1590/abd1806-4841.20163960
ISSN
0365-0596