Molecular analysis and patterns of ALT and hepatitis C virus seroconversion in haemodialysis patients with acute hepatitis

Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Massachusetts General Hospital and Harvard Medical School. Partners AIDS Research Center and Infectious Disease Division. Boston, MA, USA.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.

Abstract

Haemodialysis (HD) continues to carry the risk of hepatitis C virus (HCV) transmission, with delayed seroconversion and often normal alanine aminotransferase (ALT) values increasing the likelihood of undetected infection and thus uninterrupted spread of HCV. The aim of this study was to identify the characteristic patterns of ALT changes and seroconversion during an outbreak of HCV in a HD unit.We also wanted to establish the relationship between infecting viruses using molecular analysis.

Keywords in Portuguese

Hepatite Aguda
Transmissão nosocomial
Hemodiálise
Vírus da hepatite C

Keywords

Acute Hepatitis
Haemodialysis
Hepatitis C virus
Nosocomial transmission

Publisher

Wiley 12 Months

Citation

LAMPE, Elisabeth et al. Molecular analysis and patterns of ALT and hepatitis C virus seroconversion in haemodialysis patients with acute hepatitis. Nephrology, v. 13, p. 186-192, 2008.

DOI

10.1111/j.1440-1797.2008.00931.x

ISSN

1320-5358

Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/32739

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Copyright

Restricted access

Embargo date

2022-01-01

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