Author | Siqueira-Filha, Noemia Teixeira de | |
Author | Albuquerque, Maria de Fatima Militao de | |
Author | Rodrigues, Laura Cunha | |
Author | Legood, Rosa | |
Author | Santos, Andreia Costa | |
Access date | 2019-05-10T13:31:39Z | |
Available date | 2019-05-10T13:31:39Z | |
Document date | 2018 | |
Citation | TEIXEIRA DE SIQUEIRA-FILHA, N. et al. Economic Burden of HIV and TB/HIV Coinfection in a Middle-Income Country: A Costing Analysis alongside a Pragmatic Clinical Trial in Brazil. Sexually Transmitted Infections, v. 94, n. 6, p. 463–469, 2018. | pt_BR |
ISSN | 1472-3263 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/33032 | |
Sponsorship | Instituto de Tecnologia em Saúde Avaliação (IATS). | pt_BR |
Language | eng | pt_BR |
Rights | restricted access | pt_BR |
Title | Economic burden of HIV and TB/HIV coinfection in a middle-income country: a costing analysis alongside a pragmatic clinical trial in Brazil | pt_BR |
Type | Article | |
DOI | 10.1136/sextrans-2017-053277 | |
Abstract | Objective The objective of this study was to measure
the costs of people living with HIV (PLHIV) as well as
active tuberculosis (TB/HIV), latent tuberculosis infection
(LTBI/HIV) or without TB (HIV/AIDS).
Methods We analysed the costs through the entire
pathway of care during the prediagnosis and treatment
periods from the Brazilian public health system
perspective. We applied a combination of bottom-up and
top-down approaches to capture and estimate direct
medical and non-medical costs. We measured the mean
cost per patient per type of care (inpatient, outpatient
and emergency care) and disease category (HIV/AIDS,
HIV/AIDS death, TB/HIV, TB/HIV death and LTBI/HIV).
Results Between March 2014 and March 2016 we
recruited 239 PLHIV. During the follow-up 26 patients
were diagnosed and treated for TB and 5 received
chemoprophylaxis for LTBI. During the prediagnosis and
treatment period, the mean total costs for HIV or AIDS
and AIDS death categories were US$1558 and US$2828,
respectively. The mean total costs for TB/HIV and TB/
HIV death categories were US$5289.0 and US$8281,
respectively. The mean total cost for the LTBI/HIV
category was US$882.
Conclusions Patients with TB/HIV impose a higher
economic burden on the health system than HIV/AIDS
and LTBI/HIV. Patients with LTBI/HIV were the lowest
cost group among all disease categories, indicating that
preventive TB treatment can avoid the further costs
treating active TB. | pt_BR |
Affilliation | London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
Affilliation | London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK. | pt_BR |
Affilliation | London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK. | pt_BR |
Affilliation | London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK. | pt_BR |
Subject | Latent Tuberculosis | pt_BR |
Subject | Brazil | pt_BR |
Subject | Coinfection | pt_BR |
Subject | Cost of Illness | pt_BR |
Subject | Costs and Cost Analysis | pt_BR |
Subject | HIV Infections | pt_BR |
Subject | Health Services Research | pt_BR |
DeCS | Adulto | pt_BR |
DeCS | Brasil / epidemiologia | pt_BR |
DeCS | Coinfecção / economia | pt_BR |
DeCS | Coinfecção / epidemiologia | pt_BR |
DeCS | Custos e Análise de Custo | pt_BR |
DeCS | Fêmea | pt_BR |
DeCS | Infecções por HIV / economia | pt_BR |
DeCS | Infecções por HIV / epidemiologia | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Renda | pt_BR |
DeCS | Tuberculose Latente / epidemiologia | pt_BR |
DeCS | Masculino | pt_BR |
DeCS | Meia idade | pt_BR |
DeCS | Adulto jovem | pt_BR |
Embargo date | 2050-01-01 | |
xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |