| Author | Passos, S. R. L. | |
| Author | Bedoya, S. J. | |
| Author | Hökerberg, Y. H. M. | |
| Author | Maia, S. C. | |
| Author | Georg, I. | |
| Author | Nogueira, Rita Maria R. | |
| Author | Souza, R. V. | |
| Author | Marzochi, K. B. F. | |
| Access date | 2019-05-16T17:47:35Z | |
| Available date | 2019-05-16T17:47:35Z | |
| Document date | 2008 | |
| Citation | PASSOS, S. R. L. et al. Clinical and Laboratory Signs as Dengue Markers During an Outbreak in Rio de Janeiro. Infection, v. 36, n. 6, p. 570-574, Nov. 2008. | pt_BR |
| ISSN | 0300-8126 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/33121 | |
| Language | eng | pt_BR |
| Publisher | Springer Verlag (Germany) | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Dengue | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Subject in Portuguese | Surto | pt_BR |
| Subject in Portuguese | Marcadores | pt_BR |
| Subject in Portuguese | Sinais clínicos laboratoriais | pt_BR |
| Title | Clinical and Laboratory Signs as Dengue Markers During an Outbreak in Rio de Janeiro | pt_BR |
| Type | Article | |
| DOI | 10.1007/s15010-008-7334-6 | |
| Abstract | Background: One of the main challenges for clinical research in dengue is the low validity of clinical diagnosis. Objective: To analyze clinical and laboratory data as predicitve factors of dengue diagnosis at Evandro Chagas Clinical Research Institute, Oswaldo Cruz Foundation, during
the 2001–2002 dengue outbreak in Rio de Janeiro. Methods: Cross sectional study comparing clinical laboratory data collected from the National Information System for Compulsory Notification Diseases (SINAN) in two serologically confirmed groups: dengue D (N = 453)
and non-dengue ND (N = 80). Results: Fever, exanthema, itching, mean platelet count < 150,000, WBC count < 4,000 and absence of vomiting
and of abdominal pain help to distinguish D from ND groups. When considered individually, these signs and symptoms enhance diagnostic sensitivity and, when used in combination, improve specificity. Conclusion: A combination of symptoms not necessarily considered indicative of dengue diagnosis could improve surveillance and medical decision-making in simple clinical settings. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Clinical and Laboratory Signs | pt_BR |
| Subject | Dengue | pt_BR |
| Subject | Markers | pt_BR |
| Subject | Outbreak | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| e-ISSN | 1439-0973 | |
| Embargo date | 2022-01-01 | |
