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CANINE VISCERAL LEISHMANIASIS: DIAGNOSIS AND MANAGEMENT OF THE RESERVOIR LIVING AMONG US
Travi, Bruno L. et al. | Date Issued: 2018
Author
Travi, Bruno L.
Cordeiro-da-Silva, Anabela
Dantas-Torres, Filipe
Miró, Guadalupe
Affilliation
University of Texas Medical Branch. Department of Internal Medicine-Division of Infectious Diseases. Galveston, Texas, USA.
Universidade do Porto. Instituto de Investigação e Inovação em Saúde. Porto, Portugal / Universidade do Porto. Instituto de Biologia Molecular e Celular. Parasite Disease Group. Porto, Portugal / Universidade do Porto. Faculdade de Farmácia. Departamento de Ciências Biológicas. Porto, Portugal.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil.
Universidad Complutense de Madrid. Veterinary Faculty. Animal Health Department. Madrid, Spain.
Abstract
This article reviews essential topics of canine visceral leishmaniasis (CVL) due to Leishmania infantum infection. It focuses on the current serological and molecular diagnostic methods used in epidemiological research and veterinary clinics to diagnose CVL and includes new point-of-care (POC) tests under development. The efficacy of different treatment regimens on the clinical improvement and infectiousness of dogs is also addressed. In the last section, the review provides a critical appraisal of the effectiveness of different control measures that have been implemented to curb disease transmission.
Keywords
Leishmania infantum
Leishmaniose Visceral
Dog Diseases
 
DeCS
Alopurinol / uso terapêutico
Animais
Agentes Antiprotozoários / uso terapêutico
Reservatórios de Doenças / parasitologia
Reservatórios de Doenças / veterinária
Doenças do Cão / diagnóstico
Dog Diseases / drug therapy
Doenças do Cão / parasitologia
Cães
Leishmania infantum / efeitos de drogas
Leishmaniose Visceral / diagnóstico
Leishmaniose Visceral / parasitologia
Leishmaniose Visceral / veterinária
Meglumina / uso terapêutico
Antimoniato de Meglumina
Técnicas de Diagnóstico Molecular
Fosforilcolina / análogos e derivados
Fosforilcolina / uso terapêutico
Testes Sorológicos
 
Citation
TRAVI, Bruno L. et al. Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us. PLoS Neglected Tropical Diseases, v. 12, p. 1-13, 11 Jan. 2018.
DOI
10.1371/journal.pntd.0006082
ISSN
1935-2735