| Author | Rodrigues, Luciana Silva | |
| Author | Hacker, Mariana Andrea | |
| Author | Illarramendi Rojas, Ximena | |
| Author | Pinheiro, Maria Fernanda Miguens Castelar | |
| Author | Nery, José Augusto da Costa | |
| Author | Sarno, Euzenir Nunes | |
| Author | Pessolani, Maria Cristina Vidal | |
| Access date | 2019-07-12T18:37:56Z | |
| Available date | 2019-07-12T18:37:56Z | |
| Document date | 2011 | |
| Citation | RODRIGUES, Luciana Silva et al. Circulating levels of insulin-like growth factor-I (IGF-I) correlate with disease status in leprosy. BMC Infectious Diseases, v. 11, n. 339, p. 1-8, 2011. | pt_BR |
| ISSN | 1471-2334 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34042 | |
| Language | eng | pt_BR |
| Publisher | BMC | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Mycobacterium leprae | pt_BR |
| Subject in Portuguese | Hanseníase | pt_BR |
| Subject in Portuguese | Reações de lepra | pt_BR |
| Subject in Portuguese | Biomarcador | pt_BR |
| Subject in Portuguese | Sistema neuroendócrino | pt_BR |
| Subject in Portuguese | Resposta imune-inflamatória | pt_BR |
| Title | Circulating levels of insulin-like growth factor-I (IGF-I) correlate with disease status in leprosy | pt_BR |
| Type | Article | |
| DOI | 10.1186/1471-2334-11-339 | pt_BR |
| Abstract | Caused by Mycobacterium leprae (ML), leprosy presents a strong immune-inflammatory component, whose status dictates both the clinical form of the disease and the occurrence of reactional episodes. Evidence has shown that, during the immune-inflammatory response to infection, the growth hormone/insulin-like growth factor-I (GH/IGF-I) plays a prominent regulatory role. However, in leprosy, little, if anything, is known about the interaction between the immune and neuroendocrine systems. | en |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Microbiologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Ri de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Ri de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Laboratório Sergio Franco. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Ri de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Ri de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Microbiologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Leprosy | pt_BR |
| Subject | IGF-1 | pt_BR |
| Subject | IGFPB-3 | pt_BR |
| Subject | Leprosy reactions | pt_BR |
| Subject | Mycobacterium leprae | pt_BR |
| Subject | Biomarker | pt_BR |
| Subject | Neuroendocrine system | pt_BR |
| Subject | Immune-inflammatory response | pt_BR |
