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2020-08-16
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REPORT INTERNATIONAL: ADVANCING TUBERCULOSIS BIOMARKER RESEARCH THROUGH GLOBAL COLLABORATION
Hamilton, Carol D. et al. | Date Issued: 2015
Author
Hamilton, Carol D.
Swaminathan, Soumya
Christopher, Devasahayam J.
Ellner, Jerrold
Gupta, Amita
Sterling, Timothy R.
Rolla, Valeria
Srinivasan, Sudha
Karyana, Muhammad
Siddiqui, Sophia
Stoszek, Sonia K.
Kim, Peter
Affilliation
FHI 360. Scientific Affairs, Global Health, Population and Nutrition. Durham, NC, USA / Duke University. School of Medicine. Durham, NC, USA.
National Institute for Research in Tuberculosis. Department of Clinical Research. Chennai and Pune, India.
Christian Medical College. Pulmonary Medicine. Vellore, India.
Boston University. School of Medicine. Boston, MA, USA.
Johns Hopkins University. School of Medicine. Baltimore, MD, USA.
Vanderbilt University. School of Medicine. Department of Medicine. Division of Infectious Diseases. Nashville, TN, USA.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
National Institutes of Health. National Institute of Allergy and Infectious Diseases. Division of AIDS. Rockville, MD, USA.
National Institutes of Health. National Institute of Allergy and Infectious Diseases. Division of Clinical Research. Rockville, MD, USA / Indonesia Ministry of Health. The National Institute of Research and Development. Jakarta, Indonesia.
National Institutes of Health. National Institute of Allergy and Infectious Diseases. Division of Clinical Research. Rockville, MD, USA.
Westat. Health Studies Sector. Rockville, MD, USA.
National Institutes of Health. National Institute of Allergy and Infectious Diseases. Division of AIDS. Rockville, MD, USA.
Abstract
Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research in Tuberculosis (RePORT) International represents a consortium of regional cohorts (RePORT India, RePORT Brazil, and RePORT Indonesia) that are linked through the implementation of a Common Protocol for data and specimen collection, and are poised to address this critical research need. Each RePORT network is designed to support local, in-country tuberculosis-specific data and specimen biorepositories, and associated research. Taken together, the expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators. Additional networks are expected to be added, helping to spur tuberculosis treatment and prevention research around the world.
Keywords
Tuberculosis
Biological markers
Biological specimen banks
Prospective studies
Specimen handling
 
Publisher
Oxford University Press
Citation
HAMILTON, Carol D. et al. RePORT International: Advancing tuberculosis biomarker research through global collaboration. Clinical Infectious Diseases, v. 61, suppl. 3, p. 155-159, 2015.
DOI
10.1093/cid/civ611
ISSN
1058-4838