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INTRODUCTION OF NDM-1 AND OXA-370 FROM BRAZIL INTO CHILE IN STRAINS OF KLEBSIELLA PNEUMONIAE ISOLATED FROM A SINGLE PATIENT
Carrasco-Anabalón, Sergio et al. | Date Issued: 2019
Author
Carrasco-Anabalón, Sergio
Conceição Neto, Carlos Orlando
Carvalho-Assef, Ana Paula D 'A.
Lima, Celia A.
Cifuentes, Marcela
Silva, Francisco
Barrera, Boris
Domínguez, Mariana
González-Rocha, Gerardo
Bello-Toledo, Helia
Affilliation
Universidad de Concepción. Facultad de Ciencias Biológicas. Departamento de Microbiología. Laboratorio de Investigación en Agentes Antibacterianos. Concepción, Chile / Hospital Regional Dr. Guillermo Grant Benavente. Laboratorio Central. Concepción, Chile.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
Universidad de Concepción. Facultad de Ciencias Biológicas. Departamento de Microbiología. Laboratorio de Investigación en Agentes Antibacterianos. Concepción, Chile / Universidad de Concepción. Facultad de Medicina. Departamento de Medicina Interna. Concepción, Chile.
Hospital Clínico Universidad de Chile. Santiago, Chile.
Hospital Clínico Universidad de Chile. Santiago, Chile.
Hospital Clínico Universidad de Chile. Santiago, Chile.
Universidad de Concepción. Facultad de Ciencias Biológicas. Departamento de Microbiología. Laboratorio de Investigación en Agentes Antibacterianos. Concepción, Chile.
Universidad de Concepción. Facultad de Ciencias Biológicas. Departamento de Microbiología. Laboratorio de Investigación en Agentes Antibacterianos. Concepción, Chile / Nucleus Millennium on Interdisciplinary Approach to Antimicrobial Resistance, Microbe-R. Chile.
Universidad de Concepción. Facultad de Ciencias Biológicas. Departamento de Microbiología. Laboratorio de Investigación en Agentes Antibacterianos. Concepción, Chile.
Abstract
Carbapenemase-producing Enterobacteriaceae have rapidly disseminated worldwide and can colonize patients in healthcare centers. As in Chile the first isolations of NDM-1 and OXA-370 carbapenemases were related with a patient arriving from Brazil, the genetic relatedness of Klebsiella pneumoniae strains producers of these enzymes and isolated in both countries was assessed. PFGE analyses revealed that the isolates were clonally related, illustrating how travel contributes to the spread of multidrug-resistant microorganisms. In addition, the occurrence of three different carbapenemases in three different K. pneumoniae strains isolated from a single patient is described.
Keywords in Portuguese
NDM-1
OXA-370
Carbapenêmicos
Klebsiella pneumoniae
Resistência a múltiplas drogas
 
Keywords
NDM-1
OXA-370
Carbapenemase
Klebsiella pneumoniae
Multi-drug-resistance
 
DeCS
Carbapenêmicos
Klebsiella pneumoniae
 
Publisher
Elsevier
Citation
CARRASCO-ANABALÓN, Sergio et al. Introduction of NDM-1 and OXA-370 from Brazil into Chile in strains of Klebsiella pneumoniae isolated from a single patient. International Journal of Infectious Diseases, v. 81, p. 28–30, 2019.
DOI
10.1016/j.ijid.2019.01.051
ISSN
1201-9712