| Author | Herrera, Leidi | |
| Author | Xavier, Samanta das Chagas | |
| Author | Viegas, Claudia | |
| Author | Martinez, Clara | |
| Author | Cotias, Paulo Marcelo | |
| Author | Carrasco, Hernan | |
| Author | Urdaneta-Morales, Servio | |
| Author | Jansen, Ana Maria | |
| Access date | 2019-09-23T18:11:39Z | |
| Available date | 2019-09-23T18:11:39Z | |
| Document date | 2004 | |
| Citation | HERRERA, Leide et al. Trypanosoma cruzi in a caviomorph rodent: parasitological and pathological features of the experimental infection of Trichomys apereodes (Rodentia, Echimyidae). Experimental Parasitology, v.107, p. 78-88, 2004. | pt_BR |
| ISSN | 0014-4894 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/35813 | |
| Language | eng | pt_BR |
| Publisher | Elsevier 12 Months | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Doença de Chagas | pt_BR |
| Subject in Portuguese | Histopatologia | pt_BR |
| Subject in Portuguese | Trichomys apereoides | pt_BR |
| Subject in Portuguese | Infecção | pt_BR |
| Title | Trypanosoma cruzi in a caviomorph rodent: parasitological and pathological features of the experimental infection of Trichomys apereoides (Rodentia, Echimyidae) | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.exppara.2004.04.008 | |
| Abstract | To understand the interaction of Trypanosoma cruzi with caviomorph rodents, which supposedly have an ancient co-evolutionary history with this parasite, experimental infection of laboratory reared Trichomys apereoides with several isolates of both genotypes of the parasite was studied. Parasitemia, pattern of hematic cells, specific humoral immune response, histopathological features and parasite clearance were appraised. T. apereoides maintained stable infections independent of the T. cruzi genotype as demonstrated by positive PCR results in analyses of several tissues after a 5 months follow-up. The acute phase was characterized by abundant and disseminated presence of amastigotes, vacuolization and/or myocytolysis. Lymphocytosis was a common feature. The chronic phase was characterized mainly by lymphomacroeosinophilic infiltrates independent of the inoculated T. cruzi isolate. T. cruzi of different genotypes did not show any tissular preference in T. apereoides. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil / Central University of Venezuela. Science Faculty. Institute of Tropical Zoology. Caracas, Venezuela. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Central University of Venezuela. Medicine Faculty. Nutrition School. Caracas, Venezuela. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Central University of Venezuela. Faculty Medicine. Tropical Medicine Institute. Caracas, Venezuela. | pt_BR |
| Affilliation | Central University of Venezuela. Science Faculty. Institute of Tropical Zoology. Caracas, Venezuela. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Chagas Disease | pt_BR |
| Subject | Histopathology | pt_BR |
| Subject | Trichomys apereoides | pt_BR |
| Subject | Infection | pt_BR |
| e-ISSN | 1090-2449 | |
| Embargo date | 2025-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
