| Author | Silva, Luciana Maria | |
| Author | Pimenta, Rafael Nacif | |
| Author | Ortolani, Paula Ladeira | |
| Author | Moura, Layla Mosqueira | |
| Author | Cordeiro, Marta do Nascimento | |
| Author | Chavez-Olórtegui, Carlos | |
| Author | Pimenta, Paulo Filemon Paolucci | |
| Author | Fortes-Dias, Consuelo Latorre | |
| Access date | 2019-10-04T18:34:30Z | |
| Available date | 2019-10-04T18:34:30Z | |
| Document date | 2019 | |
| Citation | SILVA, Luciana Maria et al. Immunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy. Toxicon, v. 167, p. 168-171, 2019. | pt_BR |
| ISSN | 0041-0101 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/36201 | |
| Language | eng | pt_BR |
| Publisher | Elsevier Ltd | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Immunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.toxicon.2019.06.018 | |
| Abstract | In the last decades, main advances were achieved in the identification, structural and pharmacological characterization of Phoneutria nigriventer toxins. However, studies on the venom-producing apparatus are rare. Presently, we applied immunolabeling to historesin-embedded cross-sections of P. nigriventer venom glands. Toxins and toxin-secreting cells were successfully located in situ, using laser confocal scanning microscopy. The methodological strategy was successful and may be applied in future studies on venom glands and other secreting tissues, in general. | pt_BR |
| Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Laboratório de Entomologia Médica. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Laboratório de Entomologia Médica. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil. | pt_BR |
| Subject | Armed spider | pt_BR |
| Subject | Phoneutria nigriventer | pt_BR |
| Subject | Toxin immunodetection | pt_BR |
| Subject | Venom gland | pt_BR |
| Subject | Venom toxin secretion | pt_BR |
| Embargo date | 2022-01-01 | |
