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COMPLETE GENETIC CHARACTERIZATION OF A BRAZILIAN DENGUE VIRUS TYPE 3 STRAIN ISOLATED FROM A FATAL OUTCOME
Miagostovich, Marize Pereira et al. | Date Issued: 2006
Author
Miagostovich, Marize Pereira
Santos, Flávia Barreto dos
Fumian, Tulio Machado
Guimarães, Flávia Ramos
Costa, Eliane Veiga da
Tavares, Fernando Neto
Coelho, Janice Oliveira
Nogueira, Rita Maria Ribeiro
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.
Abstract
We have determined the complete nucleotide and the deduced amino acid sequences of Brazilian dengue virus type 3 (DENV-3) from a dengue case with fatal outcome, which occurred during an epidemic in the state of Rio de Janeiro, Brazil, in 2002. This constitutes the first complete genetic characterization of a Brazilian DENV-3 strain since its introduction into the country in 2001. DENV-3 was responsible for the most severe dengue epidemic in the state, based on the highest number of reported cases and on the severity of clinical manifestations and deaths reported.
Keywords in Portuguese
Vírus da Dengue tipo 3
Genoma completo
Brasil
 
Keywords
Dengue virus type 3
Complete genome
Brazil
 
Publisher
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
Citation
MIAGOSTOVICH, Marise Pereira et al. Complete genetic characterization of a Brazilian dengue virus type 3 strain isolated from a fatal outcome. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 101, n. 3, p. 307-313, May 2006.
DOI
10.1590/s0074-02762006000300015
ISSN
0074-0206