Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/3841
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dc.contributor.authorMendonça, Cristiane Lafetá Furtado de
dc.contributor.authorCarvalho, Omar dos Santos
dc.contributor.authorMota, Ester Maria
dc.contributor.authorMachado, Marcelo Pelajo
dc.contributor.authorCaputo, Luzia F. G.
dc.contributor.authorLenzi, Henrique Leonel
dc.date.accessioned2012-04-13T19:45:23Z
dc.date.available2012-04-13T19:45:23Z
dc.date.issued1999
dc.identifier.citationMENDONCA, Cristiane L.G.F. et al. Penetration Sites and Migratory Routes of Angiostrongylus costaricensis in the Experimental Intermediate Host (Sarasinula marginata). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.94, n.4, p. 549-556, 1999.
dc.identifier.issn0074-0276
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/3841
dc.descriptionAcknowledgements to A.L. de Amorim, FF Cruz, ID Pedro (Department of Pathology, Instituto Oswaldo Cruz) for their technical assistance.
dc.language.isoeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.rightsopen access
dc.titlePenetration sites and migratory routes of Angiostrongylus costaricensis in the experimental intermediate host (Sarasinula marginata)
dc.typeArticle
dc.identifier.doi10.1590/S0074-02761999000400022
dc.description.abstractenThe intermediate hosts of Angiostrongylus costaricensis are terrestrian molluscs, mostly of the family Veronicellidae. The present work aimed at clarifying more accurately the sites of penetration and the migratory routes of A. costaricensis in the tissue slugs and at verifying the pattern of the perilarval reaction at different times of infection. Slugs were individually infected with 5,000 L1, and killed from 30 min to 30 days after infection. From 30 min up to 2 hr after infection, L1 were found within the lumen of different segments of the digestive tube having their number diminished in more advanced times after exposition until complete disappearance. After 30 min of exposition, percutaneous infection occurred, simultaneously to oral infection. Perilarval reaction was observed from 2 hr of infection around larvae in fibromuscular layer, appearing later (after 6 hr) around larvae located in the viscera. A pre-granulomatous reaction was characterized by gradative concentration of amebocytes around larvae, evolving two well-organized granulomas. In this work we confirmed the simultaneous occurrence of oral and percutaneous infections. Perilarval reaction, when very well developed, defined typical granulomatous structure, including epithelioid cell transformation. The infection also caused a systemic mobilization of amebocytes and provoked amebocyte-endothelium interactions.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas René-Rachou. Laboratório de Helmintoses Intestinais. Belo Horizonte, MG, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas René-Rachou. Laboratório de Helmintoses Intestinais. Belo Horizonte, MG, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
dc.subject.enAngiostrongylus costaricensis
dc.subject.enGranuloma
dc.subject.enMigratory routes
dc.subject.enAmebocytes
dc.subject.enIntermediate host
dc.subject.enSarasinula marginata
dc.subject.decsAngiostrongylus
dc.subject.decsInterações Hospedeiro-Parasita
dc.subject.decsMoluscos - parasitologia
dc.subject.decsInfecções por Strongylida
Appears in Collections:MG - IRR - Artigos de Periódicos
IOC - Artigos de Periódicos

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