| Author | Aimbire, F. | |
| Author | Martins, R. A. B. Lopes | |
| Author | Faria Neto, Hugo C. | |
| Author | Albertini, R. | |
| Author | Chavantes, M. C. | |
| Author | Pacheco, M. T. T. | |
| Author | Leonardo, P. S. L. M. | |
| Author | Iversen, V. V. | |
| Author | Bjordal, J. M. | |
| Access date | 2019-12-19T16:16:12Z | |
| Available date | 2019-12-19T16:16:12Z | |
| Document date | 2006 | |
| Citation | AIMBIRE, F. et al. Low-level laser therapy can reduce lipopolysaccharide-induced contractile force dysfunction and TNF-α levels in rat diaphragm muscle. Lasers in Medical Science, v. 21, p. 238-244, 2006. | pt_BR |
| ISSN | 0268-8921 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/38717 | |
| Language | eng | pt_BR |
| Publisher | Springer Verlag (Germany) | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Doença inflamatória crônica | pt_BR |
| Subject in Portuguese | Estimulação elétrica muscular | pt_BR |
| Subject in Portuguese | Clorpromazina | pt_BR |
| Subject in Portuguese | Laser de diodo Ga – AsI – Al | pt_BR |
| Title | Low-level laser therapy can reduce lipopolysaccharide-induced contractile force dysfunction and TNF-alpha levels in rat diaphragm muscle | pt_BR |
| Type | Article | |
| DOI | 10.1007/s10103-006-0405-y | |
| Abstract | Our objective was to investigate if low-level laser therapy (LLLT) could improve respiratory function and inhibit tumor necrosis factor (TNF-alpha) release into the diaphragm muscle of rats after an intravenous injection of lipopolysaccharide (LPS) (5 mg/kg). We randomly divided Wistar rats in a control group without LPS injection, and LPS groups receiving either (a) no therapy, (b) four sessions in 24 h with diode Ga-AsI-Al laser of 650 nm and a total dose of 5.2 J/cm2, or (c) an intravenous injection (1.25 mg/kg) of the TNF-alpha inhibitor chlorpromazine (CPZ). LPS injection reduced maximal force by electrical stimulation of diaphragm muscle from 24.15+/-0.87 N in controls, but the addition of LLLT partly inhibited this reduction (LPS only: 15.01+/-1.1 N vs LPS+LLLT: 18.84+/-0.73 N, P<0.05). In addition, this dose of LLLT and CPZ significantly (P<0.05 and P<0.01, respectively) reduced TNF-alpha concentrations in diaphragm muscle when compared to the untreated control group. | pt_BR |
| Affilliation | Research Group of Animal Experimental, IP & D UNIVAP R. Shishima Hifumi. São José dos Campos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Farmacologia. Laboratório de Farmacologia e Fototerapia da Inflamação. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Research Group of Animal Experimental, IP & D UNIVAP R. Shishima Hifumi. São José dos Campos, SP, Brasil. | pt_BR |
| Affilliation | Instituto do Coração. Departamento de Laser em Biomedicina. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Research Group of Animal Experimental, IP & D UNIVAP R. Shishima Hifumi. São José dos Campos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Farmacologia. Laboratório de Farmacologia e Fototerapia da Inflamação. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | University of Bergen. Haukeland University Hospital. Department of Biomedicine. Section of Physiology. Bergen, Norway. | pt_BR |
| Affilliation | University of Bergen. Institute of Public Health and Primary Health Care. Section of Physiotherapy Science. Section of `shysiotherapy Science. Bergen, Norway / Bergen University College, Physiotherapy Department. Bergen, Norway, | pt_BR |
| Subject | Diode Ga–AsI–Al laser | pt_BR |
| Subject | Chronic inflammation disease | pt_BR |
| Subject | Chlorpromazine (CPZ) | pt_BR |
| Subject | Electrical muscle stimulation | pt_BR |
| e-ISSN | 1435-604X | |
| Embargo date | 2025-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
