| Author | Cosgrove, Catherine A. | |
| Author | Castello Branco, Luiz R. R. | |
| Author | Hussell, Tracy | |
| Author | Sexton, Amy | |
| Author | Giemza, Rafaela | |
| Author | Phillips, Richard | |
| Author | Williams, Andrew | |
| Author | Griffin, George E. | |
| Author | Dougan, Gordon | |
| Author | Lewis, David J. M. | |
| Access date | 2020-01-03T15:28:58Z | |
| Available date | 2020-01-03T15:28:58Z | |
| Document date | 2006 | |
| Citation | COSGROVE, Catherine A. et al. Boosting of Cellular Immunity against Mycobacterium tuberculosis and Modulation of Skin Cytokine Responses in Healthy Human Volunteers by Mycobacterium bovis BCG Substrain Moreau Rio de Janeiro Oral Vaccine. Infection and Immunity, v. 74, n. 4, p. 2449-2452, Apr. 2006. | pt_BR |
| ISSN | 0019-9567 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/38970 | |
| Language | eng | pt_BR |
| Publisher | American Society for Microbiology | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Imunidade celular | pt_BR |
| Subject in Portuguese | Mycobacterium tuberculosis | pt_BR |
| Subject in Portuguese | Mycobacterium bovis | pt_BR |
| Subject in Portuguese | Vacina oral | pt_BR |
| Subject in Portuguese | BCG | pt_BR |
| Subject in Portuguese | Citocinas cutâneas | pt_BR |
| Subject in Portuguese | Voluntários humanos saudáveis | pt_BR |
| Title | Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine | pt_BR |
| Type | Article | |
| DOI | 10.1128/IAI.74.4.2449-2452.2006 | |
| Abstract | Oral immunization of healthy adults with 10(7) CFU BCG Moreau Rio de Janeiro was well tolerated and significantly boosted gamma interferon responses to purified protein derivative, Ag85, and MPB70 from previous childhood intradermal BCG immunization. Oral BCG offers the possibility of a needle-free tuberculosis vaccine and of boosting the protective immunity from intradermal tuberculosis vaccines. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Fundação Ataulpho de Paiva. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Imperial College. Center for Molecular Microbiology and Immunology. London, United Kingdom. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Affilliation | Imperial College. Center for Molecular Microbiology and Immunology. London, United Kingdom. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Affilliation | Sanger Institute, Cambridge, United Kingdom. | pt_BR |
| Affilliation | St George’s Vaccine Institute. St George’s Hospital Medical School.London, United Kingdom. | pt_BR |
| Subject | Mycobacterium tuberculosis | pt_BR |
| Subject | Cellular Immunity | pt_BR |
| Subject | Mycobacterium bovis BCG | pt_BR |
| Subject | Oral vaccine | pt_BR |
| Subject | Skin Cytokine | pt_BR |
| Subject | Healthy Human Volunteers | pt_BR |
| e-ISSN | 1098-5522 | |
| Embargo date | 2025-01-01 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
