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2025-01-01
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- IOC - Artigos de Periódicos [12490]
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SEQUENTIAL BONE HEALING OF IMMEDIATELY LOADED MINI-IMPLANTS: HISTOMORPHOMETRIC AND FLUORESCENCE ANALYSIS
Cicatrização óssea
Histomorfométricos
Análise de fluorescência
Author
Affilliation
University of California-San Diego. Department of Mechanical and Aerospace Engineering. San Diego, CA, USA / Insituto Militar de Engenharia. Rio de Janeiro, RJ, Brasil.
University of California-San Diego. Department of Mechanical and Aerospace Engineering. San Diego, CA, USA / Insituto Militar de Engenharia. Rio de Janeiro, RJ, Brasil.
Insituto Militar de Engenharia. Departamento de Engenharia Mecânica e Ciência dos Materiais. Rio de Janeiro, RJ, Brasil.
University of California-San Diego. Department of Mechanical and Aerospace Engineering. San Diego, CA, USA .
Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Experimentação Animal. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Experimentação Animal. Rio de Janeiro, RJ, Brasil.
University of California-San Diego. Department of Mechanical and Aerospace Engineering. San Diego, CA, USA / Insituto Militar de Engenharia. Rio de Janeiro, RJ, Brasil.
Insituto Militar de Engenharia. Departamento de Engenharia Mecânica e Ciência dos Materiais. Rio de Janeiro, RJ, Brasil.
University of California-San Diego. Department of Mechanical and Aerospace Engineering. San Diego, CA, USA .
Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Experimentação Animal. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Experimentação Animal. Rio de Janeiro, RJ, Brasil.
Abstract
Introduction: Mini-implants are often immediately loaded for orthodontic treatment; however, changes in interfacial tissues caused by early loading and its effects might compromise the mini-implant’s function. The purpose of this study was to compare the healing of interfacial tissues 1, 4, and 12 weeks after the placement of titanium-alloy mini-implants in New Zealand rabbits; some of the implants were loaded immediately and others were left unloaded. Methods: Eighteen animals were used in the experiment. Each received 4 titanium grade 5 mini-implants (2.0 3 6.0 mm), 2 of which were immediately loaded with 1 N of force. Tissue healing was verified at 1, 4, and 12 weeks after placement. Four different fluorescent molecules were injected into the rabbits to label calcium deposition. After the rabbits were killed, mineralized bone samples with the mini-implants were removed, fixed, cut, stained, and observed with bright-field, polarized, and fluorescence microscopy. Results: After 12 weeks of healing, higher bone contact and bone area were observed than after 1 or 4 weeks, regardless of loading. Differences between the loaded and unloaded groups were not observed (P \0.05) at 1 and 4 weeks. The bone deposition rate was higher in the loaded group. Conclusions: The 1-N immediate force application did not compromise bone formation around mini-implants. (Am J Orthod Dentofacial Orthop 2010;137:80-90).
Keywords in Portuguese
Mini-implantesCicatrização óssea
Histomorfométricos
Análise de fluorescência
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