| Author | Lenzi, Henrique Leonel | |
| Author | Lenzi, Jane A. | |
| Author | Rosman, F. C. | |
| Author | Machado, Marcelo Pelajo | |
| Author | Mota, M. | |
| Author | Panasco, Monica de Souza | |
| Author | Oliveira, Denise N. | |
| Access date | 2012-05-15T14:47:55Z | |
| Available date | 2012-05-15T14:47:55Z | |
| Document date | 1995 | |
| Citation | LENZI H. L. et al. Extramedullary hematopoiesis in murine schistosomiasis mansoni. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.90, n.2, p.169-177. Apr 1995. | pt_BR |
| ISSN | 0074-0276 | |
| URI | https://www.arca.fiocruz.br/handle/icict/4069 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Title | Extramedullary hematopoiesis in murine schistosomiasis mansoni | pt_BR |
| Type | Article | |
| DOI | http://dx.doi.org/10.1590/S0074-02761995000200008 | |
| Abstract | During Schistosoma mansoni infection, there is morphological evidence of involvement of various hematopoietic growth factors, which cause eosinophil, neutrophil, megakaryocytic and erythroid extramedullary foci in the liver, lymph nodes and omental and mesenteric milky spots. While the eosinophil metaplasia in the periphery of hepatic granulomas roughly reproduced the intensity of the medullary eosinopoiesis, the neutrophil metaplasia, on the contrary, was more intense during the period of neutrophil depression in the bone marrow. This fact suggests that extramedullary hematopoietic foci are locally regulated, and amplify and/or compensate the systemic hematopoietic response during the infection. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Cosinophil | pt_BR |
| Subject | neutrophil | pt_BR |
| Subject | Megakaryocyte | pt_BR |
| Subject | Hematopoiesis | pt_BR |
| Subject | Schistosoma mansoni | pt_BR |
| Subject | Lymph nodes | pt_BR |
| Subject | Milky spots | pt_BR |
| DeCS | Schistosoma mansoni | pt_BR |
| DeCS | Infecção | pt_BR |
| DeCS | Megacariócitos | pt_BR |
| DeCS | Hematopoese | pt_BR |
| DeCS | Linfonodos | pt_BR |
