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FIRST DETECTION AND MOLECULAR CHARACTERIZATION OF A DENV-1/DENV-4 CO-INFECTION DURING AN EPIDEMIC IN RIO DE JANEIRO, BRAZIL
Nogueira, Fernanda de Bruycker et al. | Date Issued: 2018
Author
Nogueira, Fernanda de Bruycker
Faria, Nieli Rodrigues da Costa
Nunes, Priscila Conrado Guerra
Nogueira, Rita Maria Ribeiro
Filippis, Ana Maria Bispo de
Santos, Flavia Barreto dos
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.
Abstract
In the 80s, dengue viruses type 1 and 4 (DENV-1 and 4) were isolated in North region of Brazil. However, it was only after the DENV-1 introduction in the state of Rio de Janeiro (RJ) in mid-1980s, that dengue became a nationwide public health problem. In 2009, this serotype re-emerged causing an explosive epidemic in the country. DENV-4 was first detected in RJ in 2011 and in 2012, and DENV-1 and 4 were co-circulating and responsible for a high number of cases notifications. Here, we describe the detection and molecular characterization of a DENV-1/4 co-infection in sample of 2012 in RJ.
Keywords in Portuguese
Co-infecção
Vírus da Dengue tipo 1
Vírus da Dengue tipo 4
Genótipo II
Genótipo V
 
Keywords
Co-infection
Dengue virus 1
Dengue virus 4
Genotype II
Genotype V
 
Publisher
Wiley
Citation
NOGUEIRA, Fernanda de Bruycker; et al. First detection and molecular characterization of a DENV1/DENV-4 co-infection during an epidemic in Rio de Janeiro, Brazil. Clinical Case Reports, v. 6, p. 2075-2080, 2018.
DOI
10.1002/ccr3.1750
ISSN
2050-0904