Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/4089
Title: Phenotypic plasticity in adult worms of Schistosoma mansoni (Trematoda:Schistosomatidae) evidenced by brightfield and confocal laser scanning microscopies
Authors: Neves, Renata Heisler
Silva, Michele Costa
Martinez, Elaine Machado
Branquinho, Thiago B.
Oliveira, Regina Maria Figueiredo de
Lenzi, Henrique Leonel
Gomes, Delir Corrêa
Silva, José Roberto Machado e
Affilliation: Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia e Laboratórios. Disciplina de Parasitologia. Rio de Janeiro, RJ, Brasil
Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia e Laboratórios. Disciplina de Parasitologia. Rio de Janeiro, RJ, Brasil
Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia e Laboratórios. Disciplina de Parasitologia. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia e Laboratórios. Disciplina de Parasitologia. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Helmintos Parasitos de Vertebrados, Departamento de Helmintologia. Rio de Janeiro, RJ, Brasil
Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Patologia e Laboratórios. Disciplina de Parasitologia. Rio de Janeiro, RJ, Brasil
Abstract: A comparative morphometric study was performed to identify host-induced morphological alterations in Schistosoma mansoni adult worms. A wild parasite population was obtained from a naturally infected rodent (Nectomys squamipes)and then recovered from laboratory infected C3H/He mice. Furthermore, allopatric worm populations maintained for long-term under laboratory conditions in Swiss Webster mice were passed on to N. squamipes. Suckers and genital system (testicular lobes, uterine egg, and egg spine) were analyzed by a digital system for image analysis. Confocal laser scanning microscopy (CLSM) showed details of the genital system (testicular lobes, vitelline glands, and ovary) and the tegument just below the ventral sucker. Significant morphological changes (p < 0.05) were detected in male worms in all experimental conditions, with no significant variability as assessed by CLSM. Significant changes (p < 0.05) were evident in females from the wild population related to their ovaries and vitelline glands, whereas allopatric females presented differences only in this last character. We conclude that S. mansoni worms present the phenotypic plasticity induced by modifications in the parasite's microenvironment, mainly during the first passage under laboratory conditions.
Keywords: Schistosoma mansoni
phenotypic plasticity
Adult worms
Nectomys squamipes
C3H/He mice
confocal laser scanning microscopy
DeCS: Schistosoma mansoni, anatomia & histologia
Microscopia Confocal
Fenótipo
Issue Date: 2004
Publisher: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
Citation: Neves, Renata Heisler et al. Phenotypic plasticity in adult worms of Schistosoma mansoni (Trematoda:Schistosomatidae) evidenced by brightfield and confocal laser scanning microscopies. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 2, p. 131-136, mar. 2004.
DOI: 10.1590/S0074-02762004000200003
ISSN: 0074-0276
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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