| Author | Lenzi, Jane A. | |
| Author | Machado, Marcelo Pelajo | |
| Author | Mota, Ester Maria | |
| Author | Oliveira, Denise N. | |
| Author | Panasco, Monica de Souza | |
| Author | Andrade, Zilton de Araújo | |
| Author | Lenzi, Henrique Leonel | |
| Access date | 2012-05-28T17:52:02Z | |
| Available date | 2012-05-28T17:52:02Z | |
| Document date | 1998 | |
| Citation | LENZI, Jane A. et al. Effects of Schistosomal mansoni infection on Calomys callosus coelom-associated lymphomyeloid tissue (milky spots). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.93, sup.1, p.13-23, 1998. | pt_BR |
| ISSN | 0074-0276 | |
| URI | https://www.arca.fiocruz.br/handle/icict/4100 | |
| Description | Acknowledgemetns to A. L. de Amorim, FF Cruz, ID Pedro and LFG Caputo for their technical assistance. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Title | Effects of Schistosomal Mansoni Infection on Calomys callosus Coelom-associated Lymphomyeloid Tissue (Milky Spots) | pt_BR |
| Type | Article | |
| Abstract | Calomys callosus Rengger, 1830 (Rodentia: Cricetidae) is a mouse-like South American wild rodent, which is permissive to Schistosoma mansoni infection. In this paper we studied the effect of schistosomal infection in C. callosus mesenteric and omental milky spots (MS), subsidiary foci of coelom-associated lymphomyeloid tissue (CALT), during the acute, transitional (acute to chronic), and chronic phases of the infection. MS were morphologically analyzed by histological methods, using brigthfield and confocal laser scanning microscopies. The MS of infected animals were mainly of lymphomyelocytic (42 to 90 days) and lymphoplasmacytic (160 days of infection) types and showed frequent presence of lymphoid follicles with germinal centers, plasmacytogenesis and plasmacytosis, mastocytosis, megakaryopoiesis, erythropoiesis and less pronounced eosinopoiesis. These results indicate that MS are a preferential site of germinal-center-dependent and independent plasmacytogenesis, and a bone marrow-like organ, committed with various cellular lineages. The consequence of C. callosus MS reactivity for schistosomal infection is still unknown and is under investigation. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz, Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Calomys callosus | pt_BR |
| Subject | coelom-associated lymphomyeloid tissue (CALT) | pt_BR |
| Subject | Schistosoma mansoni | pt_BR |
| Subject | Milky spots | pt_BR |
| Subject | Omentum | pt_BR |
| Subject | Laser confocal microscopy | pt_BR |
| DeCS | Schistosoma mansoni | pt_BR |
| DeCS | Omento | pt_BR |
| DeCS | Tecido linfóide | pt_BR |
| DeCS | Patologia | |
