| Author | Noske, Gabriela Dias | |
| Author | Gawriljuk, Victor Oliveira | |
| Author | Fernandes, Rafaela Sachetto | |
| Author | Furtado, Nathalia Dias | |
| Author | Bonaldo, Myrna Cristina | |
| Author | Oliva, Glaucius | |
| Author | Godoy, Andre Schutzer | |
| Access date | 2020-05-05T19:14:40Z | |
| Available date | 2020-05-05T19:14:40Z | |
| Document date | 2020 | |
| Citation | NOSKE, Gabriela Dias et al. Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus. BBA-General Subjects, v.1864, 129521, 11p, Jan. 2020. | pt_BR |
| ISSN | 0304-4165 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/41130 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Víirus da Febre Amarela | pt_BR |
| Subject in Portuguese | Flavivírus | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Subject in Portuguese | Protease | pt_BR |
| Subject in Portuguese | NS3 | pt_BR |
| Subject in Portuguese | NS2B | pt_BR |
| Title | Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.bbagen.2020.129521 | |
| Abstract | The Yellow Fever virus (YFV) is transmitted by mosquitos and causes an infection with symptoms including fever, headaches and nausea. In 20–50% of the cases, the disease may evolve to a visceral stage, reaching high mortality rates. YFV NS2B-NS3 protease has been identified as an important drug target | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Flavivírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Flavivírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, SP, Brasil. | pt_BR |
| Subject | Yellow fever virus | pt_BR |
| Subject | Flavivirus | pt_BR |
| Subject | Potease | pt_BR |
| Subject | NS3 | pt_BR |
| Subject | NS2B | pt_BR |
| Subject | Brazil | pt_BR |
| Embargo date | 2025-01-01 | |
