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THE MOLLUSCICIDAL ACTIVITY OF NICLOSAMIDE (BAYLUSCIDE WP70®) ON MELANOIDES TUBERCULATA (THIARIDAE), A SNAIL ASSOCIATED WITH HABITATS OF BIOMPHALARIA GLABRATA (PLANORBIDAE)
Biomphalaria glabrata
Esquistossomose
Niclosamida
Moluscicida
Author
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Politécnica de Saúde Joaquim Venâncio. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Politécnica de Saúde Joaquim Venâncio. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Rio de Janeiro, RJ, Brasil.
Abstract
The aim of this study was to determine the toxicity of niclosamide (Bayluscide ®) on Melanoides tuberculata and
Biomphalaria glabrata under laboratory conditions. The latter species is the intermediate host of Schistosoma
mansoni (Sambon 1917). M. tuberculata was successfully used as competitor of B. glabrata in biological control
programs in French West Indies. Both molluscicide and biological control using M. tuberculata have proved to be
successful in reducing the population density of B. glabrata. The associated use of molluscicide in this area would
be an effective measure if M. tuberculata were less susceptibility to the molluscicide than B. glabrata. Three hundreds
individuals each of B. glabrata and of M. tuberculata, collected in Sumidouro, State of Rio de Janeiro, were used
in the experiment. The molluscs were exposed to 14 different concentrations of niclosamide as recommended by the
World Health Organization. Probit analysis was used to determine the LC 50 and LC 90. The LC 50 and LC 90 values
for B. glabrata were 0.077 mg/l and 0.175 mg/l, respectively and the LC 50 and LC 90 values for M. tuberculata were
0.082 mg/l and 0.221 mg/l respectively. As the lethal concentrations of niclosamide were approximately the same to
both species, this could be a disadvantage when controlling B. glabrata with niclosamide in an area of M. tuberculata
occurrence. It migth therefore be preferable to utilize the latex extracted from the Euphorbia splendens, which
presented a much higher efficiency for B. glabrata than to M. tuberculata.
Keywords in Portuguese
Melanoides tuberculataBiomphalaria glabrata
Esquistossomose
Niclosamida
Moluscicida
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