| Author | Machado, Paulo Roberto Lima | |
| Author | Penna, Gerson Oliveira | |
| Access date | 2020-05-25T13:46:58Z | |
| Available date | 2020-05-25T13:46:58Z | |
| Document date | 2012 | |
| Citation | MACHADO, Paulo R.L.; PENNA, Gerson. Miltefosine and cutaneous leishmaniasis. Current Opinion in Infectious Diseases, [s.l], v. 25, p. 141–144, 2012. | pt_BR |
| ISSN | 0951-7375 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/41371 | |
| Description | Gerson Oliveira Penna - Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento do vinculo com a unidade da Fiocruz Brasília. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Lippincott, Williams & Wilkins | pt_BR |
| Rights | restricted access | pt_BR |
| MeSH | Administration, Oral | pt_BR |
| MeSH | Antiprotozoal Agents | pt_BR |
| MeSH | Clinical Trials as Topic | pt_BR |
| MeSH | Leishmaniasis | pt_BR |
| MeSH | Phosphorylcholine | pt_BR |
| Title | Miltefosine and cutaneous leishmaniasis | pt_BR |
| Type | Article | |
| DOI | 10.1097/QCO.0b013e3283509cac | |
| Abstract | Purpose of review Miltefosine is a new oral treatment against leishmaniasis. The evidence about its use in New and Old World cutaneous leishmaniasis is presented and discussed. Recent findings Miltefosine is being tested with small clinical trials mainly in endemic cutaneous leishmaniasis regions of South America and Iran. Severe cutaneous leishmaniasis forms successfully treated with miltefosine are reported. Summary The use of miltefosine in cutaneous leishmaniasis has been addressed in a few clinical trials. An important advantage of this drug is its oral administration when compared with the standard parenteral drugs in the context of a large-scale use in the inner regions of the endemic countries. Miltefosine also shows activity in severe or refractory cases. However, this review points out the need for further investment on clinical research into cutaneous leishmaniasis treatment. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Hospital Universitário Prof. Edgard Santos. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Universidade de Brasília. Faculdade de Medicina. Núcleo de Medicina Tropical. Brasília, DF, Brasil / Fundação Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. | pt_BR |
| Subject | Cutaneous leishmaniasis | pt_BR |
| Subject | Diffuse cutaneous leishmaniasis | pt_BR |
| Subject | Disseminated leishmaniasis | pt_BR |
| Subject | Miltefosine | pt_BR |
| Subject | Mucosal leishmaniasis | pt_BR |
| DeCS | Leishmaniose | pt_BR |
| DeCS | Leishmaniose Cutânea | pt_BR |
| DeCS | Leishmaniose Tegumentar Difusa | pt_BR |
| DeCS | Antiprotozoários | pt_BR |
| DeCS | Ensaios Clínicos como Assunto | pt_BR |
| DeCS | Resultado do Tratamento | pt_BR |
| Embargo date | 2025-12-31 | |
