Author | Golbert, Daiane C. F. | |
Author | Lacerda, Leandra Linhares | |
Author | Almeida, Luiz G. | |
Author | Santana, Eliane Correa de | |
Author | Oliveira, Alice R. de | |
Author | Mundstein, Alex S. | |
Author | Savino, Wilson | |
Author | Vasconcelos, Ana T. R. de | |
Access date | 2020-07-03T17:57:32Z | |
Available date | 2020-07-03T17:57:32Z | |
Document date | 2011 | |
Citation | GOLBERT, Daiane C. F. et al. Laminin database: a tool to retrieve high-throughput and curated data for studies on laminins. Nucleic Acids Research, v. 39, p. D320-D323, 17 Nov. 2011. Supplement 1. | pt_BR |
ISSN | 0305-1048 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/42064 | |
Language | eng | pt_BR |
Publisher | Oxford University Press | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Banco de dados de lamininas | pt_BR |
Subject in Portuguese | Alta produtividade | pt_BR |
Subject in Portuguese | Ferramenta | pt_BR |
Subject in Portuguese | Estudos sobre lamininas | pt_BR |
Title | Laminin database: a tool to retrieve high-throughput and curated data for studies on laminins | pt_BR |
Type | Article | pt_BR |
DOI | 10.1093/nar/gkq1055 | pt_BR |
Abstract | The Laminin(LM)-database, hosted at http://www.lm.lncc.br, is the first database focusing a noncollagenous extracellular matrix protein family, the LMs. Part of the knowledge available in this website is automatically retrieved, whereas a significant amount of information is curated and annotated, thus placing LM-database beyond a simple repository of data. In its home page, an overview of the rationale for the database is seen and readers can access a tutorial to facilitate navigation in the website, which in turn is presented with tabs subdivided into LMs, receptors, extracellular binding and other related proteins. Each tab opens into a given LM or LM-related molecule, where the reader finds a series of further tabs for ‘protein’, ‘gene structure’, ‘gene expression’ and ‘tissue distribution’ and ‘therapy’. Data are separated as a function of species, comprising Homo sapiens, Mus musculus and Rattus novergicus. Furthermore, there is specific tab displaying the LM nomenclatures. In another tab, a direct link to PubMed, which can be then consulted in a specific way, in terms of the biological functions of each molecule, knockout animals and genetic diseases, immune response and lymphomas/leukemias. LM-database will hopefully be a relevant tool for retrieving information concerning LMs in health and disease, particularly regarding the hemopoietic system. | en |
Affilliation | Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil. | pt_BR |
Affilliation | Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil. | pt_BR |
Subject | Laminin database | en |
Subject | High-throughput | en |
Subject | Tool | en |
Subject | Studies on laminins | en |
e-ISSN | 1362-4962 | pt_BR |