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TRANSMISSION OF CHIKUNGUNYA VIRUS IN AN URBAN SLUM, BRAZIL
Virus Chikungunya
Epidemics
Infecção assimtomática
Brasil
Soroprevalência
Chikungunya virus
Epidemia
Asymptomatic infection
Brazil
Seroprevalence
Author
Affilliation
Abstract
After a chikungunya outbreak in Salvador, Brazil, we performed a cross-sectional, community-based study of 1,776 inhabitants to determine chikungunya virus (CHIKV) seroprevalence, identify factors associated with exposure, and estimate the symptomatic infection rate. From November 2016 through February 2017, we collected sociodemographic and clinical data by interview and tested serum samples for CHIKV IgG. CHIKV seroprevalence was 11.8% (95% CI 9.8%-13.7%), and 15.3% of seropositive persons reported an episode of fever and arthralgia. Infections were independently and positively associated with residences served by unpaved streets, a presumptive clinical diagnosis of chikungunya, and recall of an episode of fever with arthralgia in 2015-2016. Our findings indicate that the chikungunya outbreak in Salvador may not have conferred sufficient herd immunity to preclude epidemics in the near future. The unusually low frequency of symptomatic disease points to a need for further longitudinal studies to better investigate these findings.
Keywords in Portuguese
ArboviralVirus Chikungunya
Epidemics
Infecção assimtomática
Brasil
Soroprevalência
Keywords
Arboviral infectionChikungunya virus
Epidemia
Asymptomatic infection
Brazil
Seroprevalence
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