Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/42231

Type
Article
Copyright
Open access
Sustainable Development Goals
10 Redução das desigualdades
14 Vida na água
 
Collections
Share

Statistics
Metadata
Show full item record

GLOBAL OCEAN RESISTOME REVEALED: EXPLORING ANTIBIOTIC RESISTANCE GENE ABUNDANCE AND DISTRIBUTION IN TARA OCEANS SAMPLES
Cuadrat, Rafael R. C. et al. | Date Issued: 2020
Author
Cuadrat, Rafael R. C.
Sorokina, Maria
Andrade, Bruno G.
Goris, Tobias
Dávila, Alberto M. R.
Affilliation
Department of Molecular Epidemiology. German Institute of Human Nutrition Potsdam-Rehbruecke - DIfE, Arthur-Scheunert-Allee 114–116, 14558 Nuthetal, Germany.
Friedrich-Schiller University. Institute for Inorganic and Analytical Chemistry. Lessingstrasse 8, 07743 Jena, Germany.
EMBRAPA. Laboratório de Biotecnologia Animal. Embrapa Pecuária Sudeste. São Carlos, SP, Brasil.
Department of Molecular Toxicology, Research Group Intestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke - DIfE, Arthur-Scheunert-Allee 114–116, 14558 Nuthetal, Germany.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Computacional e de Sistemas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Programa de Pós-Graduação em Biodiversidade e Saúde. Rio de Janeiro, RJ, Brasil.
Abstract
The rise of antibiotic resistance (AR) in clinical settings is of great concern. Therefore, the understanding of AR mechanisms, evolution, and global distribution is a priority for patient survival. Despite all efforts in the elucidation of AR mechanisms in clinical strains, little is known about its prevalence and evolution in environmental microorganisms. We used 293 metagenomic samples from the TARA Oceans project to detect and quantify environmental antibiotic resistance genes (ARGs) using machine learning tools.
Keywords in Portuguese
Abundância de ARGs
Diversidade
Amostras metagenômicas
Projeto TARA Oceans
 
Keywords
Diversity
Abundance of ARGs
TARA Oceans project
Global ocean metagenome
 
Publisher
Oxford University Press
Citation
CUADRAT, Rafael R. C. et al. Global ocean resistome revealed: Exploring antibiotic resistance gene abundance and distribution in TARA Oceans samples. Giga Science, v. 9, p. 1-12, 2020.
DOI
10.1093/gigascience/giaa046
ISSN
2047-217X