| Author | Silva, Adriana R. | |
| Author | Moraes, Bianca P. T. | |
| Author | Albuquerque, Cassiano F. Gonçalves de | |
| Access date | 2020-07-31T19:53:10Z | |
| Available date | 2020-07-31T19:53:10Z | |
| Document date | 2020 | |
| Citation | SILVA, Adriana R.; MORAES, Bianca P. T.; ALBUQUERQUE, Cassiano F. Gonçalves de. Mediterranean Diet: Lipids, Inflammation, and Malaria Infection. International Journal of Molecular Science, v. 21, n. 4489, p. 1-22, 2020. | pt_BR |
| ISSN | 1661-6596 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/42496 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Malária | pt_BR |
| Subject in Portuguese | Inflamação | pt_BR |
| Subject in Portuguese | Dieta mediterrânea | pt_BR |
| Subject in Portuguese | Ácido graxo | pt_BR |
| Subject in Portuguese | Õmega-3 | pt_BR |
| Subject in Portuguese | Õmega-9 | pt_BR |
| Subject in Portuguese | Õmega-6 | pt_BR |
| Title | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection | pt_BR |
| Type | Article | |
| DOI | 10.3390/ijms21124489 | |
| Abstract | The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions of people around the globe. The parasite Plasmodium causes the disease. The metabolic and inflammatory alterations in the severe forms have damaging consequences to the host. The lipid content in the MedDiet holds anti-inflammatory and pro-resolutive features in the host and have detrimental effects on the Plasmodium. The lipids from the diet impact the balance of pro- and anti-inflammation, thus, lipids intake from the diet is critical to parasite elimination and host tissue damage caused by an immune response. Herein, we go into the cellular and molecular mechanisms and targets of the MedDiet fatty acids in the host and the parasite, reviewing potential benefits of the MedDiet, on inflammation, malaria infection progression, and clinical outcome. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Universidade Federal Fluminense. Programa de Neurociências. Niterói, RJ, Brasil / Fundação Oswaldo Cruz. Instittuto Oswaldo Cruz. Programa de Pós-Graduação em Biologia Celular e Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Universidade Federal Fluminense. Programa de Neurociências. Niterói, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Universidade Federal Fluminense. Programa de Neurociências. Niterói, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Programa de Pós-Graduação em Biologia Molecular e Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Mediterranean diet | pt_BR |
| Subject | Fatty acid | pt_BR |
| Subject | Omega-3 | pt_BR |
| Subject | Omega-6 | pt_BR |
| Subject | Omega-9 | pt_BR |
| Subject | Inflammation | pt_BR |
| Subject | Malaria | pt_BR |
| e-ISSN | 1422-0067 | |
