| Author | Silveira, Melise Chaves | |
| Author | Souza, Cláudio Marcos Rocha de | |
| Author | Albano, Rodolpho Mattos | |
| Author | Santos, Ivson Cassiano de Oliveira | |
| Author | Carvalho-Assef, Ana Paula D'Alincourt | |
| Access date | 2020-08-06T18:10:55Z | |
| Available date | 2020-08-06T18:10:55Z | |
| Document date | 2020 | |
| Citation | SILVEIRA, Melise Chaves et al. Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C. BMC Genomics, v. 21, n. 255, p. 1-8, 2020. | pt_BR |
| ISSN | 1471-2164 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/42576 | |
| Language | eng | pt_BR |
| Publisher | BMC | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Pseudomonas aeruginosa | pt_BR |
| Subject in Portuguese | ST277 | pt_BR |
| Subject in Portuguese | CRISPR | pt_BR |
| Subject in Portuguese | Genômica comparativa | pt_BR |
| Title | Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C | pt_BR |
| Type | Article | |
| DOI | 10.1186/s12864-020-6650-9 | |
| Abstract | The Brazilian endemic clone Pseudomonas aeruginosa ST277 carries important antibiotic resistance determinants, highlighting the gene coding for SPM-1 carbapenemase. However, the resistance and persistence of this clone is apparently restricted to the Brazilian territory. To understand the differences between Brazilian strains from those isolated in other countries, we performed a phylogenetic analysis of 47 P. aeruginosa ST277 genomes as well as analyzed the virulence and resistance gene profiles. Furthermore, we evaluated the distribution of genomic islands and assessed in detail the characteristics of the CRISPR-Cas immunity system in these isolates. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade do Estado do Rio de Janeiro. Departamento de Bioquímica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Pseudomonas aeruginosa | pt_BR |
| Subject | ST277 | pt_BR |
| Subject | CRISPR | pt_BR |
| Subject | Comparative genomics | pt_BR |
