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TRYPANOSOMA CRUZI INFECTION IN LEONTOPITHECUS ROSALIA AT THE RESERVA BIOLÓGICA DE POÇO DAS ANTAS, RIO DE JANEIRO, BRAZIL
Leontopithecus rosalia
Ciclo silvestre
Perfis de eletroforese
Brasil
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Rio de Janeiro, RJ, Brasil.
University of Maryland. Department of Zoology. College Park, MD, USA.
Philadelphia Zoological Garden. Philadelphia, USA.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Genética. Rio de Janeiro, RJ, Brasil.
University of Maryland. Department of Zoology. College Park, MD, USA.
Philadelphia Zoological Garden. Philadelphia, USA.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Genética. Rio de Janeiro, RJ, Brasil.
Abstract
Wild golden lion tamarins (Leontopithecus rosalia) – endangered primates that are native to the
Brazilian Atlantic coastal forest – were surveyed for the presence of Trypanosoma cruzi with the use of
Giemsa-stained blood smears, hemocultures and an indirect immunofluorescence assay (IFAT). Positive
IFAT with titers ranging from 1:20 to 1:1280 were observed in 52% of the 118 wild tamarins examined
and the parasite was isolated from 38 tamarins. No patent parasitemia was observed among the tamarins
from which T. cruzi was isolated. Serum conversion and positive hemoculture was observed for three
animals that had yielded negative results some months earlier, which indicates that T. cruzi is actively
transmitted among tamarins. In contrast to observations with other sylvatic isolates, those from the
tamarins were significantly more virulent and most of them produced mortality in experimentally infected
Swiss mice. Some variation in the kDNA restriction profiles among the isolates was observed.
Electrophoresis with GPI, G6PDH, IDH, MDH and ME enzymes showed a Z2 profile.
Keywords in Portuguese
Trypanosoma cruziLeontopithecus rosalia
Ciclo silvestre
Perfis de eletroforese
Brasil
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