| Author | Silva, Walter A. Eyer | |
| Author | Bello, Gonzalo | |
| Author | Morgado, Mariza G. | |
| Access date | 2020-11-22T20:08:14Z | |
| Available date | 2020-11-22T20:08:14Z | |
| Document date | 2007 | |
| Citation | SILVA, Walter A. Eyer; BELLO. Gonzalo; MORGADO, Mariza G. Molecular evidence that human immunodeficiency virus type 1 dissemination in a small Brazilian city was already taking place in the early 1990s. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 102, n. 5, p. 647-649, Aug. 2007. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44580 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | AIDS | pt_BR |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Vírus da imunodeficiência humana tipo 1 | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Molecular evidence that human immunodeficiency virus type 1 dissemination in a small Brazilian city was already taking place in the early 1990s | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762007000500018 | |
| Abstract | We recently performed a molecular epidemiology survey of human immunodeficiency virus type 1 (HIV-1) infection in Miracema, a small city in Southeast Brazil, and found multiple monophyletic clusters, consistent with independent introductions and spread of different viral lineages in the city. Here we apply Bayesian coalescent-based methods to the two largest subtype B clusters and estimate that the most recent common ancestors that gave rise to these two transmission chains were in circulation around 1991-1992. The finding that HIV-1 spread in this Brazilian small city was already taking place at a time Aids was considered a problem restricted to large urban centers may have important public health implications. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Aids & Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil / Programa Municipal de HIV/Aids de Miracema, Miracema, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Aids & Imunologia Molecular. Rio de Janeiro, RJ, Brasil; | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Aids & Imunologia Molecular. Rio de Janeiro, RJ, Brasil; | pt_BR |
| Subject | AIDS | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | Human immunodeficiency virus type 1 | pt_BR |
| Subject | Brazil | pt_BR |
| e-ISSN | 1678-8060 | |
