| Author | Bonomo, Adriana C. | |
| Author | Mariz, Fernanda Pinto | |
| Author | Riederer, Ingo | |
| Author | Benjamin, Claudia F. | |
| Author | Butler-Browne, Gillian | |
| Author | Mouly, Vincent | |
| Author | Savino, Wilson | |
| Access date | 2021-01-09T19:23:05Z | |
| Available date | 2021-01-09T19:23:05Z | |
| Document date | 2020 | |
| Citation | BONOMO, Adriana C. et al. Crosstalk Between Innate and T Cell Adaptive Immunity With(in) the Muscle. Frontiers in Physiology, v. 11, Article 573347, p. 1-11, Sept. 2020. | pt_BR |
| ISSN | 1664-042X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/45547 | |
| Language | eng | pt_BR |
| Publisher | Frontiers Media | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Mioblastos | pt_BR |
| Subject in Portuguese | Macrófagos | pt_BR |
| Subject in Portuguese | Células dendríticas | pt_BR |
| Subject in Portuguese | Células T efetoras | pt_BR |
| Subject in Portuguese | Células T regulatórias | pt_BR |
| Subject in Portuguese | Polimiosite | pt_BR |
| Subject in Portuguese | Distrofia muscular de Duchenne | pt_BR |
| Title | Crosstalk Between Innate and T Cell Adaptive Immunity With(in) the Muscle | pt_BR |
| Type | Article | |
| DOI | 10.3389/fphys.2020.573347 | |
| Abstract | Growing evidence demonstrates a continuous interaction between the immune system
and the skeletal muscle in inflammatory diseases of different pathogenetic origins, in
dystrophic conditions such as Duchenne Muscular Dystrophy as well as during normal
muscle regeneration. Although one component of the innate immunity, the macrophage,
has been extensively studied both in disease conditions and during cell or gene therapy
strategies aiming at restoring muscular functions, much less is known about dendritic
cells and their primary immunological targets, the T lymphocytes. This review will focus
on the dendritic cells and T lymphocytes (including effector and regulatory T-cells),
emphasizing the potential cross talk between these cell types and their influence on
the structure and function of skeletal muscle. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rede Nacional de Pesquisa em Neuroimflamação. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Pediatria Martagão Gesteira. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rede Nacional de Pesquisa em Neuroimflamação. Rio de Janeiro, RJ, Brasil / School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, United Kingdom. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rede Nacional de Pesquisa em Neuroimflamação. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Programa de Imunobiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Sorbonne Université, Inserm, Institut de Myologie, U974, Center for Research in Myology. Paris, France. | pt_BR |
| Affilliation | Sorbonne Université, Inserm, Institut de Myologie, U974, Center for Research in Myology. Paris, France. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rede Nacional de Pesquisa em Neuroimflamação. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Myoblasts | pt_BR |
| Subject | Macrophages | pt_BR |
| Subject | Dendritic cells | pt_BR |
| Subject | Effector T cells | pt_BR |
| Subject | Regulatory T cells | pt_BR |
| Subject | Polymyositis | pt_BR |
| Subject | Duchenne muscular dystrophy | pt_BR |
