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Sustainable Development Goals
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AMOUNT OF PHYSICAL ACTIVITY NECESSARY FOR A NORMAL LEVEL OF HIGH-SENSITIVITY C-REACTIVE PROTEIN IN ELSA-BRASIL: A CROSS-SECTIONAL STUDY
Fatores de risco
Curva ROC
Doenças cardiovasculares
Inflamação
Exercícios
Doenças crônicas
Risk factors
ROC curve
Cardiovascular diseases
Inflammation
Exercises
Chronic diseases
ELSA-Brasil
Author
Affilliation
Escola Bahiana de Medicina e Saúde Pública. Department of Physical Education. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Postgraduate Program in Biotechnology in Health and Investigative Medicine. Salvador, BA, Brasil.
Universidade Federal da Bahia. Department of Physical Education. Salvador, BA, Brasil.
Universidade de São Paulo. Clinical and Epidemiological Research Center. São Paulo, SP, Brazil.
Universidade Federal do Espirito Santo. Public Health Program. Vitória, ES, Brazil.
Universidade Federal da Bahia. Institute of Collective Health. Salvador, BA, Brazil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Public Health Researcher. Salvador, BA, Brazil.
Universidade Federal da Bahia. Department of Physical Education. Salvador, BA, Brasil.
Universidade de São Paulo. Clinical and Epidemiological Research Center. São Paulo, SP, Brazil.
Universidade Federal do Espirito Santo. Public Health Program. Vitória, ES, Brazil.
Universidade Federal da Bahia. Institute of Collective Health. Salvador, BA, Brazil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Public Health Researcher. Salvador, BA, Brazil.
Abstract
BACKGROUND: Studies have shown that physical activity levels can be inversely associated with high-sensitivity
C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain
normal hs-CRP levels is still a matter for speculation.
OBJECTIVE: To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults.
DESIGN AND SETTING: Cross-sectional study at six teaching and research institutions.
METHODS: The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the
Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves
were constructed to compare the amount of physical activity in two domains (leisure time and commuting)
with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical
activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).
RESULTS: The area under the ROC curve was only statistically significant for discriminating normal levels of
hs-CRP according to the amount of physical activity when the two study domains were added together.
The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal
levels of hs-CRP in adults of both sex.
CONCLUSIONS: Physical activity in the leisure-time and commuting domains together, of duration
200 minutes/week, was associated with normal hs-CRP values.
Keywords in Portuguese
Atividade motoraFatores de risco
Curva ROC
Doenças cardiovasculares
Inflamação
Exercícios
Doenças crônicas
Keywords
Motor activityRisk factors
ROC curve
Cardiovascular diseases
Inflammation
Exercises
Chronic diseases
ELSA-Brasil
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