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NEURODEVELOPMENT IN THE THIRD YEAR OF LIFE IN CHILDREN WITH ANTENATAL ZIKV-EXPOSURE
Aizawa, Carolina Yuri Panvequio et al. | Date Issued: 2021
Author
Aizawa, Carolina Yuri Panvequio
Caron, Deyse Mayara Rodrigues
Souza, Carolina Barbosa de
Kozima, Paula Fernanda Augusto
Damasceno, Luana
Einspieler, Christa
Marschik, Peter B.
Brasil, Patrícia
Schmitt, Ana Carolina Basso
Nielsen-Saines, Karin
Hasue, Renata Hydee
Affilliation
Universidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, Brasil.
Universidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, Brasil.
Universidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, Brasil.
Universidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, Brasil.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Medical University of Graz. Division of Phoniatrics. iDN - interdisciplinary Developmental Neuroscience. Graz, Austria.
Medical University of Graz. Division of Phoniatrics. iDN - interdisciplinary Developmental Neuroscience. Graz, Austria / University Medical Center Göttingen & Leibniz ScienceCampus Primate Cognition. Child and Adolescent Psychiatry and Psychotherapy. Göttingen, Germany / Karolinska Institute. Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health. Stockholm, Sweden.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Universidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, Brasil.
University of California Los Angeles. David Geffen School of Medicine. Department of Pediatrics. Los Angeles, CA, USA.
Universidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, Brasil.
Abstract
We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015-2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.
Keywords
Child Development
Language Development
Cognition
Motor Activity
Zika Virus
 
Publisher
Scielo
Citation
AIZAWA, Carolina Yuri Panvequio et al. Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure. Revista de saúde publica, v. 55, n. 15, p. 1-6, Apr. 2021.
DOI
10.11606/s1518-8787.2021055002798
ISSN
0034-8910