Purpose: Understanding long-term patterns of suicide methods can inform public health policy and prevention strategies. In Brazil, frearm-related policies may be one salient target for suicide prevention. This study describes trends in methodspecifc suicide at the national and state-levels in Brazil, with a particular focus on frearm-related suicides. Methods: Brazilian mortality data for suicide and undetermined intent among people aged 10 years and older between 2000 and 2017 were obtained from the National Mortality Information System. We examined national and state-level trends in age-standardised suicide rates for hanging, self-poisoning, frearms, jumping from a high place, other, and unspecifed methods. We also compared total rates of mortality from suicide and undetermined intent over the period. Applying Joinpoint regression, we tested changes in trends of frearm-specifc suicide rates. Results: The total suicide rate increased between 2000 and 2017. Rates of hanging, self-poisoning by drugs or alcohol and jumping from a high place showed the largest increases, while frearm-specifc suicide rates decreased over the study period. Trends in methods of suicide varied by sex and state. Conclusion: It is of public health concern that suicide rates in Brazil have risen this millennium. Restricting access to frearms might be an efective approach for reducing frearm-specifc suicides, especially in states where frearm availability remains particularly high. Treatment and management of substance misuse may also be an important target for suicide prevention policies. More work is needed to understand the causes of rising suicide rates in Brazil and to improve the mental health of the population.