| Author | Zeng, Congli | |
| Author | Ribeiro, Gabriel C. Motta | |
| Author | Hinoshita, Takuga | |
| Author | Lessa, Marcos Adriano | |
| Author | Winkler, Tilo | |
| Author | Gorgg, Kira | |
| Author | Kingston, Nathan M. | |
| Author | Hutchinson, John N. | |
| Author | Sholl, Lynette Marie | |
| Author | Fang, Xiangming | |
| Author | Varelas, Xaralabos | |
| Author | Layne, Matthew D. | |
| Author | Baron, Rebecca M. | |
| Author | Melo, Marcos F. Vidal | |
| Access date | 2021-07-19T17:55:04Z | |
| Available date | 2021-07-19T17:55:04Z | |
| Document date | 2020 | |
| Citation | ZENG, Congli et al. Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep. Anesthesiology, v. 133, n. 5, 17 p, Nov. 2020. | pt_BR |
| ISSN | 1528-1175 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/48282 | |
| Language | eng | pt_BR |
| Publisher | American Society of Anesthesiologists | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Atelectasia pulmonar | pt_BR |
| Subject in Portuguese | Promove Imune e barreira disfunção | pt_BR |
| Subject in Portuguese | Seqüenciamento de transcriptoma | pt_BR |
| Subject in Portuguese | Ovelhas | pt_BR |
| Title | Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep | pt_BR |
| Type | Article | |
| DOI | 10.1097/ALN.0000000000003491 | |
| Abstract | Pulmonary atelectasis is frequent in clinical settings. Yet there
is limited mechanistic understanding and substantial clinical and biologic contro versy on its consequences. The authors hypothesize that atelectasis produces local
transcriptomic changes related to immunity and alveolar–capillary barrier function
conducive to lung injury and further exacerbated by systemic inflammation. | pt_BR |
| Affilliation | Massachusetts General Hospital. Department of Anesthesia, Critical Care and Pain Medicine. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Pós-Graduação e Pesquisa em Engenharia. Rio de janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Tokyo Medical and Dental University. Department of Intensive Care Medicine. Tokyo, Japan. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Massachusetts General Hospital. Department of Anesthesia, Critical Care and Pain Medicine. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Department of Radiology. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Boston University School of Medicine. Department of Biochemistry. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Harvard Chan School of Public Health. Department of Biostatistics. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Harvard Medical School. Brigham and Women’s Hospital. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Zhejiang University School of Medicine. The First Affiliated Hospital. Department of Anesthesiology. Hangzhou, China. | pt_BR |
| Affilliation | Boston University School of Medicine. Department of Biochemistry. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Boston University School of Medicine. Department of Biochemistry. Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Harvard Medical School. Brigham and Women’s Hospital. Department of Medicine (Pulmonary and Critical Care). Boston, Massachusetts, USA. | pt_BR |
| Affilliation | Massachusetts General Hospital. Department of Anesthesia, Critical Care and Pain Medicine Boston, Massachusetts, USA. | pt_BR |
| Subject | Lung Atelectasis | pt_BR |
| Subject | Promote Barrier Dysfunction | pt_BR |
| Subject | Promote Imune Dysfunction | pt_BR |
| Subject | Female Sheep | pt_BR |
| Subject | Transcriptome Sequencing | pt_BR |
| Embargo date | 2023 | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
