Please use this identifier to cite or link to this item:
Type
ArticleCopyright
Open access
Collections
- IOC - Artigos de Periódicos [12973]
Metadata
Show full item record
TRYPANOSOMA RANGELI GENETIC, MAMMALIAN HOSTS, AND GEOGRAPHICAL DIVERSITY FROM FIVE BRAZILIAN BIOMES
Mamíferos
Ecologia de parasitas
Linhagens
Biomas brasileiros
Author
Affilliation
Abstract
Abstract: Trypanosoma rangeli is a generalist hemoflagellate that infects mammals and is transmitted
by triatomines around Latin America. Due to its high genetic diversity, it can be classified into two
to five lineages. In Brazil, its distribution outside the Amazon region is virtually unknown, and
knowledge on the ecology of its lineages and on host species diversity requires further investigation.
Here, we analyzed 57 T. rangeli samples obtained from hemocultures and blood clots of 1392 mammals
captured in different Brazilian biomes. The samples were subjected to small subunit (SSU) rDNA
amplification and sequencing to confirm T. rangeli infection. Phylogenetic inferences and haplotype
networks were reconstructed to classify T. rangeli lineages and to infer the genetic diversity of
the samples. The results obtained in our study highlighted both the mammalian host range and
distribution of T. rangeli in Brazil: infection was observed in five new species (Procyon cancrivorous,
Priodontes maximum, Alouatta belzebul, Sapajus libidinosus, and Trinomys dimidiatus), and transmission
was observed in the Caatinga biome. The coati (Nasua nasua) and capuchin monkey (S. libidinosus)
are the key hosts of T. rangeli. We identified all four T. rangeli lineages previously reported in Brazil
(A, B, D, and E) and possibly two new genotypes.
Keywords in Portuguese
Trypanosoma rangeliMamíferos
Ecologia de parasitas
Linhagens
Biomas brasileiros
Share