| Author | Brooker, Simon | |
| Author | Botelho, Anne Jardim | |
| Author | Quinnell, Rupert J. | |
| Author | Geiger, Stefan Michael | |
| Author | Caldas, Iramaya R. | |
| Author | Fleming, Fiona | |
| Author | Hotez, Peter J. | |
| Author | Oliveira, Rodrigo Correa de | |
| Author | Rodrigues, Laura C. | |
| Author | Bethony, Jeffrey Michael | |
| Access date | 2022-01-03T17:47:17Z | |
| Available date | 2022-01-03T17:47:17Z | |
| Document date | 2007 | |
| Citation | BROOKER, Simon et al. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg, v. 101, n. 2, p. 146-154, 2007 . doi: 10.1016/j.trstmh.2006.05.012. | pt_BR |
| ISSN | 0035-9203 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/50601 | |
| Language | eng | pt_BR |
| Publisher | Royal Society of Tropical Medicine and Hygiene | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.trstmh.2006.05.012 | |
| Abstract | Surprisingly few detailed age-stratified data exist on the epidemiology of hookworm and iron status, especially in Latin America. We present data from a cross-sectional. survey examining 1332 individuals aged 0-86 years from a community in south-east Brazil for hookworm, anaemia and iron deficiency. Sixty-eight percent of individuals were infected with the human hookworm Necator americanus. The force of infection (lambda = 0.354) was similar to estimates from other areas of high hookworm transmission. Individuals from poorer households had significantly higher prevalence and intensity of infection than individuals from better-off households. The prevalence of anaemia, iron deficiency and iron-deficiency anaemia was 11.8%, 12.7% and 4.3%, respectively. Anaemia was most prevalent among young children and the elderly. Univariate analysis showed that haemoglobin and serum ferritin were both significantly negatively associated with hookworm intensity among both school-aged children and adults. Multivariate analysis showed that, after controlling for socio-economic status, iron indicators were significantly associated with heavy hookworm infection. Our results indicate that, even in areas where there is a low overall prevalence of anaemia, hookworm can still have an important impact on host iron status, especially in school-aged children and the elderly. (C) 2006 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved | pt_BR |
| Affilliation | Department of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine. London, UK | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | School of Biology. University of Leeds. Leeds LS2 9JT. UKd Department of Microbiology and Tropical Medicine. The George Washington University. Washington DC, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil/Department of Microbiology and Tropical Medicine. The George Washington University. Washington DC, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Department of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine. London, UK | pt_BR |
| Affilliation | Department of Microbiology and Tropical Medicine. The George Washington University. Washington DC, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Department of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine. London, UK | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, Brazil/Department of Microbiology and Tropical Medicine. The George Washington University. Washington DC, USA | pt_BR |
| Subject | hookworms | pt_BR |
| Subject | Necator americanus | pt_BR |
| Subject | hookworm infection | pt_BR |
| Subject | anaemia | pt_BR |
| Subject | iron deficiency | pt_BR |
| Subject | Brazil | pt_BR |
