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SARS-COV- 2 B.1.1.7 VARIANT OF CONCERN DETECTED IN A PET DOG AND CAT AFTER EXPOSURE TO A PERSON WITH COVID-19, USA
Author
Hamer, Sarah A.
Ghai, Ria R.
Zecca, Italo B.
Auckland, Lisa D.
Roundy, Christopher M.
Davila, Edward
Busselman, Rachel E.
Tang, Wendy
Pauvolid-Corrêa, Alex
Killian, Mary Lea
Jenkins-Moore, Melinda
Torchetti, Mia Kim
Austerman, Suelee Robbe
Lim, Ailam
Akpalu, Yao
Fischer, Rebecca S. B.
Behravesh, Casey Barton
Hamer, Gabriel L.
Ghai, Ria R.
Zecca, Italo B.
Auckland, Lisa D.
Roundy, Christopher M.
Davila, Edward
Busselman, Rachel E.
Tang, Wendy
Pauvolid-Corrêa, Alex
Killian, Mary Lea
Jenkins-Moore, Melinda
Torchetti, Mia Kim
Austerman, Suelee Robbe
Lim, Ailam
Akpalu, Yao
Fischer, Rebecca S. B.
Behravesh, Casey Barton
Hamer, Gabriel L.
Affilliation
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vpirus Respiratório e do Sarampo. Laboratório de Referência Nacional e e Regional nas Américas (PAHO/WHO). Rio de Janeiro, RJ, Brasil.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
Wisconsin Veterinary Diagnostic Laboratory, University of Wisconsin-Madison. Madison, WI, USA.
Brazos County Health Department, Bryan. TX, USA.
School of Public Health, Texas A&M University, College Station. TX, USA.
National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station. TX, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vpirus Respiratório e do Sarampo. Laboratório de Referência Nacional e e Regional nas Américas (PAHO/WHO). Rio de Janeiro, RJ, Brasil.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA, USA.
Wisconsin Veterinary Diagnostic Laboratory, University of Wisconsin-Madison. Madison, WI, USA.
Brazos County Health Department, Bryan. TX, USA.
School of Public Health, Texas A&M University, College Station. TX, USA.
National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA, USA.
Department of Entomology, Texas A&M University and AgriLife Research, College Station. TX, USA.
Abstract
As part of a longitudinal household transmission study of pets living with persons with COVID-19 in Texas, two pets were confirmed to be infected with the SARS-CoV- 2 B.1.1.7 variant of concern (VOC). The pets were a dog and a cat from the same household, sampled two days after their owner tested positive for COVID-19. The oral, nasal and fur swabs for both pets tested positive for SARS-CoV- 2 by qRT-PCR and consensus whole-genome sequences from the dog and cat were 100% identical and matched the B.1.1.7 VOC. Virus was isolated from the cat's nasal swab. One month after initial detection of infection, the pets were re-tested twice at which time only the fur swabs (both pets) and oral swab (dog only) remained positive, and neutralizing antibodies for SARS-CoV- 2 were present in both animals. Sneezing by both pets was noted by the owner in the weeks between initial and follow-up testing. This study documents the first detection of B.1.1.7. in companion animals in the United States, and the first genome recovery and isolation of B.1.1.7 variant of concern globally in any animal.
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